RP 40749: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 3034005 |
| CHEMBL ID | 100424 |
| SCHEMBL ID | 389796 |
| MeSH ID | M0106280 |
| Synonym |
|---|
| CHEMBL100424 |
| picartamide |
| rp-40749 |
| rp 40749 |
| n-methyl-2-pyridin-2-ylthiolane-2-carbothioamide |
| picartamida [spanish] |
| unii-7jz930h2m6 |
| einecs 278-531-4 |
| picartamide [inn] |
| 7jz930h2m6 , |
| picartamidum [latin] |
| (+-)-tetrahydro-n-methyl-2-(2-pyridyl)thio-2-thiophenecarboxamide |
| 2-thiophenecarbothioamide, tetrahydro-n-methyl-2-(2-pyridinyl)- |
| picartamidum |
| picartamida |
| n-methyl-2-(2-pyridyl)-2,3,4,5-tetrahydro-2-thiophene carbothioamide |
| 40749 rp |
| 76732-75-7 |
| 2-methylaminocarbothioyl-2-(pyridyl)-2-tetrahydrothiophene |
| (+/-)-tetrahydro-n-methyl-2-(2-pyridyl)thio-2-thiophenecarboxamide |
| picartamide [mart.] |
| n-methyl-2-(pyrid-2-yl)tetrahydrothiophene-2-carbothioamide |
| ITNLONMDUMHEOK-UHFFFAOYSA-N |
| SCHEMBL389796 |
| Z1509546298 |
| Q27268425 |
| n-methyl-2-(pyridin-2-yl)thiolane-2-carbothioamide |
| DTXSID30868413 |
| EN300-255609 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "The purpose of this work was to compare the effects of a long acting antisecretory drug on 24-h gastric acidity after acute and chronic administration and to correlate the results observed with modifications of pharmacokinetic parameters." | ( Acute and chronic 24-hour gastric pH and pharmacokinetic studies with a long acting antisecretory drug (40749 RP) in peptic ulcer. Bonfils, S; Denis, P; Frydman, A; Galmiche, JP; Garcia del Risco, F; Mignon, M; Piat, M; Teule, M, 1986) | 0.27 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID178849 | Antisecretory activity against histamine stimulated gastric acid secretion in Shay rats expressed as ED50 value ranges from (0.1-1.3) | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1 | Synthesis and antisecretory and antiulcer activities of derivatives and analogues of 2-(2-pyridyl)tetrahydrothiophene-2-carbothioamide. |
| AID188523 | Antiulcer activity by protection of restraint-induced gastric erosions in rats, by using the technique of Rossi was determined at peroral dose of 4.5 mg/kg | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1 | Synthesis and antisecretory and antiulcer activities of derivatives and analogues of 2-(2-pyridyl)tetrahydrothiophene-2-carbothioamide. |
| AID176292 | Antiulcer activity against histamine stimulated gastric acid secretion in Shay rats expressed as ED50 | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1 | Synthesis and antisecretory and antiulcer activities of derivatives and analogues of 2-(2-pyridyl)tetrahydrothiophene-2-carbothioamide. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 14 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.36) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 6 (40.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (60.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||