Page last updated: 2024-11-13
pyridovericin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
pyridovericin: from Beauveria bassiana; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 54697562 |
| CHEMBL ID | 4073814 |
| MeSH ID | M0294429 |
Synonyms (7)
| Synonym |
|---|
| nsc753974 |
| nsc-753974 |
| pyridovericin |
| 210976-24-2 |
| DTXSID70716000 |
| 4-hydroxy-3-[(2e,4e)-6-(hydroxymethyl)-4-methylocta-2,4-dienoyl]-5-(4-hydroxyphenyl)pyridin-2(1h)-one |
| CHEMBL4073814 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (6)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1460831 | Inhibition of ABHD12 in mouse BV2 cells preincubated for 30 mins and subsequent addition of [3H]-2-OG substrate measured after 15 mins by liquid scintillation counting method | 2017 | Bioorganic & medicinal chemistry, 11-15, Volume: 25, Issue:22 | Biological evaluation of pyridone alkaloids on the endocannabinoid system. |
| AID1460829 | Inhibition of MAGL in pig brain homogenates using [3H]2-OG as substrate at 10 uM after 15 mins in presence of URB597 by liquid scintillation counting method | 2017 | Bioorganic & medicinal chemistry, 11-15, Volume: 25, Issue:22 | Biological evaluation of pyridone alkaloids on the endocannabinoid system. |
| AID1460834 | Inhibition of FAAH in human U937 cells assessed as decrease in [ethanolamine-1-3H]AEA uptake at 10 uM preincubated for 2 mins followed by AEA addition after 5 mins by liquid scintillation counting method | 2017 | Bioorganic & medicinal chemistry, 11-15, Volume: 25, Issue:22 | Biological evaluation of pyridone alkaloids on the endocannabinoid system. |
| AID1460830 | Inhibition of ABHD6 in mouse BV2 cells preincubated for 30 mins and subsequent addition of [3H]-2-OG substrate measured after 15 mins by liquid scintillation counting method | 2017 | Bioorganic & medicinal chemistry, 11-15, Volume: 25, Issue:22 | Biological evaluation of pyridone alkaloids on the endocannabinoid system. |
| AID1460821 | Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHOK1 cell membranes at 1 uM after 2 hrs by liquid scintillation counting method relative to control | 2017 | Bioorganic & medicinal chemistry, 11-15, Volume: 25, Issue:22 | Biological evaluation of pyridone alkaloids on the endocannabinoid system. |
| AID1460823 | Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes at 1 uM after 2 hrs by liquid scintillation counting method relative to control | 2017 | Bioorganic & medicinal chemistry, 11-15, Volume: 25, Issue:22 | Biological evaluation of pyridone alkaloids on the endocannabinoid system. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.55
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.55) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||