Page last updated: 2024-12-06
premazepam
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Description
premazepam: less extensively metabolized in the rat than in the dog; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 72104 |
| CHEMBL ID | 2104741 |
| SCHEMBL ID | 414548 |
| MeSH ID | M0122525 |
Synonyms (28)
| Synonym |
|---|
| pyrrolo(3,4-e)(1,4)diazepin-2(1h)-one, 3,7-dihydro-6,7-dimethyl-5-phenyl- |
| 3,7-dihydro-6,7-dimethyl-5-phenylpyrrolo(3,4-e)-1,4-diazepin-2(1h)-one |
| nsc 290940 |
| mdl 181 |
| premazepamum [inn-latin] |
| brn 0617435 |
| 3,7-dihydro-6,7-dimethyl-5-phenylpyrrolo(3,4-e)(1,4)diazepin-2(1h)-one |
| 6,7-dimethyl-5-phenyl-1,3-dihydropyrrolo[3,4-e][1,4]diazepin-2-one |
| 6,7-dimethyl-5-phenyl-3,7-dihydropyrrolo[3,4-e][1,4]diazepin-2(1h)-one |
| dl-181 , |
| mdl-181 |
| premazepam |
| 57435-86-6 |
| nsc-290940 |
| nsc290940 |
| CHEMBL2104741 |
| unii-oi7443pdlb |
| premazepamum |
| premazepam [inn:ban] |
| oi7443pdlb , |
| AKOS015904184 |
| premazepam [inn] |
| SCHEMBL414548 |
| 3,7-dihydro-6,7-dimethyl-5-phenylpyrrolo[3,4-e][1,4]diazepin-2(1h)-one |
| CNWSHOJSFGGNLC-UHFFFAOYSA-N |
| DTXSID60206026 |
| (z)-6,7-dimethyl-5-phenylpyrrolo[3,4-e][1,4]diazepin-2(1h,3h,7h)-one |
| Q7240235 |
Research Excerpts
Pharmacokinetics
| Excerpt | Reference | Relevance |
|---|---|---|
| " The plasma curve was described by an open one-compartment model, and half-life was 11." | ( Pharmacokinetics and metabolism of premazepam, a new potential anxiolytic, in humans. Assandri, A; Bernareggi, A; Buniva, G; Fuccella, LM; Palumbo, R; Perazzi, A; Vitiello, B, 1984) | 0.54 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||