Page last updated: 2024-11-06
n-nitrosothiazolidine
Description
N-nitrosothiazolidine is a heterocyclic compound that has been studied for its potential carcinogenic properties. It is formed as a byproduct of the reaction of thiazolidine with nitrous acid, which can occur under conditions of high nitrite concentration. The compound has been detected in various food products, such as cured meats, smoked fish, and beer, and has been shown to be mutagenic in bacterial assays. Research on N-nitrosothiazolidine focuses on understanding its formation pathways, its toxicity and potential carcinogenicity, and methods for reducing its levels in food. The compound's importance lies in its potential health risks and the need to develop strategies for minimizing human exposure.'
N-nitrosothiazolidine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 52687 |
| CHEBI ID | 7329 |
| MeSH ID | M0124711 |
Synonyms (15)
| Synonym |
|---|
| 73870-33-4 |
| n-nitroso-1,3-thiazolidine |
| 3-nitrosothiazolidine |
| ccris 5493 |
| n-nitrosothiazolidine |
| thiazolidine, 3-nitroso- |
| 3-nitroso-1,3-thiazolidine |
| AKOS006272878 |
| DTXSID70224458 |
| CHEBI:7329 |
| PROHBUGJUQHONA-UHFFFAOYSA-N |
| 3-nitroso-1,3-thiazolidine # |
| ag-g-92849 |
| n-nitrosothiazolidin |
| Q27107476 |
Drug Classes (2)
| Class | Description |
|---|
| nitrosamine | N-Nitroso amines, compounds of the structure R2NNO. Compounds RNHNO are not ordinarily isolable, but they, too, are nitrosamines. The name is a contraction of N-nitrosoamine and, as such, does not require the N locant. |
| thiazolidines | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (12)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 11.38
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 11.38 (24.57) | | Research Supply Index | 2.77 (2.92) | | Research Growth Index | 4.15 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 15 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |