| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
benzene
[no description available] | 6.96 | 1 | 0 | aromatic annulene;
benzenes;
volatile organic compound | carcinogenic agent;
environmental contaminant;
non-polar solvent |
triaziquone
Triaziquone: Alkylating antineoplastic agent used mainly for ovarian tumors. It is toxic to skin, gastrointestinal tract, bone marrow and kidneys.. triaziquone : A member of the class of 1,4-benzoquinones that is 1,4-benzoquinone in which three of the ring hydrogens are replaced by aziridin-1-yl groups. | 1.96 | 1 | 0 | 1,4-benzoquinones;
aziridines | alkylating agent;
antineoplastic agent |
maleimide
[no description available] | 6.96 | 1 | 0 | dicarboximide;
maleimides | EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor |
razoxane
Razoxane: An antimitotic agent with immunosuppressive properties. | 2.41 | 2 | 0 | N-alkylpiperazine | |
etoposide
[no description available] | 1.99 | 1 | 0 | beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound | antineoplastic agent;
DNA synthesis inhibitor |
dexrazoxane
Dexrazoxane: The (+)-enantiomorph of razoxane. | 2.25 | 1 | 0 | razoxane | antineoplastic agent;
cardiovascular drug;
chelator;
immunosuppressive agent |
1,2-bis(3,5-dioxopiperazin-1-yl)ethane
[no description available] | 2.01 | 1 | 0 | | |
icrf 193
4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione: structure given in first source; RN given refers to cpd without isomeric designation. ICRF-193 : An N-alkylpiperazine that is butane which is substituted by a 3,5-dioxopiperazin-1-yl group at positions 2 and 3. The meso isomer. | 2.41 | 2 | 0 | | |
terephthalamidine
terephthalamidine: structure given in first source | 1.96 | 1 | 0 | | |
3-deazauridine
3-Deazauridine: 4-Hydroxy-1-(beta-D-ribofuranosyl)-2-pyridinone. Analog of uridine lacking a ring-nitrogen in the 3-position. Functions as an antineoplastic agent. | 1.96 | 1 | 0 | N-glycosyl compound | |