Page last updated: 2024-12-09
icd 1578
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
7-N-phenylcarbamoylamino-4-chloro-3-propyloxyisocoumarin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 577033 |
CHEMBL ID | 140958 |
SCHEMBL ID | 7311335 |
MeSH ID | M0292560 |
Synonyms (13)
Synonym |
---|
7-phenylureido-4-chloro-3-propyloxyisocoumarin |
CHEMBL140958 |
00541o72ry , |
icd-1578 |
140653-02-7 |
urea, n-(4-chloro-1-oxo-3-propoxy-1h-2-benzopyran-7-yl)-n'-phenyl- |
unii-00541o72ry |
SCHEMBL7311335 |
NTIRQLXQCVZDJU-UHFFFAOYSA-N |
4-chloro-7-(3-phenylureido)-3-(propyloxy)-1h-2-benzopyran-1-one |
n-(4-chloro-1-oxo-3-propoxy-1h-isochromen-7-yl)-n'-phenylurea # |
7-n-phenylcarbamoylamino-4-chloro-3-propyloxyisocoumarin |
Q27231318 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (5)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID52459 | The second order inactivation rate constant was expressed as inhibition of chymotrypsin (ChT). Inhibitor concentrations were 3.4-70 uM | 1995 | Journal of medicinal chemistry, Feb-03, Volume: 38, Issue:3 | Mechanism-based isocoumarin inhibitors for human leukocyte elastase. Effect of the 7-amino substituent and 3-alkoxy group in 3-alkoxy-7-amino-4-chloroisocoumarins on inhibitory potency. |
AID155080 | The second order inactivation rate constant was expressed as inhibition of porcine pancreatic elastase (PPE). Inhibitor concentrations were 34-56 uM | 1995 | Journal of medicinal chemistry, Feb-03, Volume: 38, Issue:3 | Mechanism-based isocoumarin inhibitors for human leukocyte elastase. Effect of the 7-amino substituent and 3-alkoxy group in 3-alkoxy-7-amino-4-chloroisocoumarins on inhibitory potency. |
AID67482 | Inhibition of human leukocyte elastase(HLE) at 0.7-1.7 uM | 1995 | Journal of medicinal chemistry, Feb-03, Volume: 38, Issue:3 | Mechanism-based isocoumarin inhibitors for human leukocyte elastase. Effect of the 7-amino substituent and 3-alkoxy group in 3-alkoxy-7-amino-4-chloroisocoumarins on inhibitory potency. |
AID42661 | In vitro inhibitory potency was tested against botulinum neurotoxin/B (BoNT/B) expressed as Ki | 2003 | Journal of medicinal chemistry, Oct-23, Volume: 46, Issue:22 | Development of potent inhibitors of botulinum neurotoxin type B. |
AID23826 | Rate of deacylation in porcine pancreatic elastase (PPE). | 1995 | Journal of medicinal chemistry, Feb-03, Volume: 38, Issue:3 | Mechanism-based isocoumarin inhibitors for human leukocyte elastase. Effect of the 7-amino substituent and 3-alkoxy group in 3-alkoxy-7-amino-4-chloroisocoumarins on inhibitory potency. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.87
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.87) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (20.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 4 (80.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |