| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347153 | Confirmatory screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347161 | Confirmatory screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347167 | Vero cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347149 | Furin counterscreen qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347168 | HepG2 cells viability qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347169 | Tertiary RLuc qRT-PCR qHTS assay for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347152 | Confirmatory screen NINDS AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID259227 | Ability to induce CYP1A1 protein expression in resistant human breast cancer cell line MCF7 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. |
| AID361975 | Displacement of [3H]tetrachlorodibenzo-p-dioxin from aryl hydrocarbon receptor in CRL:WI rat liver cytosol | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). |
| AID678011 | Cell cycle arrest in human COLO205 cells assessed as accumulation at G2/M phase at 16 uM after 24 hrs by FACS analysis (Rvb = 23.09 +/- 1.01%) | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID678001 | Cytotoxicity against human MCF10A cells after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID259228 | Ability to induce CYP1A1 protein expression in resistant human breast cancer cell line MDA468 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. |
| AID266703 | Antiproliferative activity against human HCT116 cell line | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| Structural studies on bioactive compounds. 40.(1) Synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzot |
| AID678010 | Cell cycle arrest in human COLO205 cells assessed as accumulation at G2/M phase at 8 uM after 24 hrs by FACS analysis (Rvb = 23.09 +/- 1.01%) | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID678007 | Cell cycle arrest in human COLO205 cells assessed as accumulation at G1 phase at 16 uM after 24 hrs by FACS analysis (Rvb = 71.02 +/- 1.00%) | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID259224 | Antiproliferative activity against human breast cancer cell line MDA468 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. |
| AID361973 | Cell cycle arrest in estrogen receptor deficient human MDA468 cells assessed as accumulation at G2/M phase at 0.1 uM after 72 hrs by flow cytometry | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). |
| AID361968 | Antiproliferative activity against estrogen receptor positive human MCF7 cells after 72 hrs by MTT assay | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). |
| AID361976 | Antiproliferative activity against human estrogen receptor positive MCF7 cells after 72 hrs by MTT assay in presence of aryl hydrocarbon receptor antagonist alpha-naphthoflavone | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). |
| AID266702 | Antiproliferative activity against human HT29 cell line | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| Structural studies on bioactive compounds. 40.(1) Synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzot |
| AID678000 | Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID259225 | Antiproliferative activity against human colon cancer cell line KM12 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. |
| AID678003 | Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID678004 | Induction of apoptosis in human COLO205 cells assessed as accumulation at G0 phase at 8 uM after 24 hrs by FACS analysis (Rvb = 2.28%) | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID361977 | Antiproliferative activity against estrogen receptor deficient human MDA468 cells after 72 hrs by MTT assay in presence of aryl hydrocarbon receptor antagonist alpha-naphthoflavone | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). |
| AID678005 | Induction of apoptosis in human COLO205 cells assessed as accumulation at G0 phase at 16 uM after 24 hrs by FACS analysis (Rvb = 2.28%) | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID259223 | Antiproliferative activity against human breast cancer cell line MCF7 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. |
| AID266701 | Antiproliferative activity against human MCF7 cell line | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| Structural studies on bioactive compounds. 40.(1) Synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzot |
| AID259230 | Ability to induce CYP1A1 protein expression in sensitive human colon cancer cell line HCC2998 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. |
| AID259226 | Antiproliferative activity against human colon cancer cell line HCC2998 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. |
| AID678006 | Cell cycle arrest in human COLO205 cells assessed as accumulation at G1 phase at 8 uM after 24 hrs by FACS analysis (Rvb = 71.02 +/- 1.00%) | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID259229 | Ability to induce CYP1A1 protein expression in sensitive human colon cancer cell line KM12 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. |
| AID678008 | Cell cycle arrest in human COLO205 cells assessed as accumulation at S phase at 8 uM after 24 hrs by FACS analysis (Rvb = 3.56 +/- 0.40%) | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID361969 | Antiproliferative activity against estrogen receptor deficient human MDA468 cells after 72 hrs by MTT assay | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). |
| AID678002 | Cytotoxicity against human A549 cells after 24 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID361971 | Cell cycle arrest in estrogen receptor deficient human MDA468 cells assessed as accumulation at G2/M phase at 0.1 uM after 24 hrs by flow cytometry | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). |
| AID678009 | Cell cycle arrest in human COLO205 cells assessed as accumulation at S phase at 16 uM after 24 hrs by FACS analysis (Rvb = 3.56 +/- 0.40%) | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17
| Synthesis and biological evaluation of novel triazoles and isoxazoles linked 2-phenyl benzothiazole as potential anticancer agents. |
| AID266700 | Antiproliferative activity against human MDA-MB-468 cell line | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| Structural studies on bioactive compounds. 40.(1) Synthesis and biological properties of fluoro-, methoxyl-, and amino-substituted 3-phenyl-4H-1-benzopyran-4-ones and a comparison of their antitumor activities with the activities of related 2-phenylbenzot |
| AID361972 | Cell cycle arrest in estrogen receptor deficient human MDA468 cells assessed as accumulation at G2/M phase at 0.1 uM after 48 hrs by flow cytometry | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |