Page last updated: 2024-12-08
docloxythepin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
docloxythepin: RN given refers to unlabeled cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 151604 |
| CHEMBL ID | 3246256 |
| MeSH ID | M0071768 |
Synonyms (12)
| Synonym |
|---|
| docloxythepin |
| 4-(2-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-1-piperazineethanol |
| 1-piperazineethanol, 4-(2-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)- |
| vufb-10032 |
| brn 0900422 |
| 2-[4-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)piperazin-1-yl]ethanol |
| 56934-18-0 |
| CHEMBL3246256 |
| 2-[4-(2-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-1-piperazinyl]ethanol |
| AE-641/00771014 |
| DTXSID60972375 |
| 2-[4-(2-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazin-1-yl]ethan-1-ol |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (5)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1136386 | Toxicity in ip dosed Sprague-Dawley rat assessed as induction of maximum catalepsy | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Neuroleptics related to butaclamol. An investigation of the effects of chlorine substituents on the aromatic rings. |
| AID1136384 | Neuroleptic activity in ip dosed Sprague-Dawley rat assessed as dose required to decrease the continuous (Sidman) lever-pressing response to <50% | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Neuroleptics related to butaclamol. An investigation of the effects of chlorine substituents on the aromatic rings. |
| AID1136382 | Neuroleptic activity in ip dosed Sprague-Dawley rat assessed as inhibition of amphetamine-induced stereotyped behaviour administered 15 mins after d-amphetamine challenge | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Neuroleptics related to butaclamol. An investigation of the effects of chlorine substituents on the aromatic rings. |
| AID1136383 | Neuroleptic activity in ip dosed Sprague-Dawley rat assessed as conditioned active avoidance failure after 30 mins | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Neuroleptics related to butaclamol. An investigation of the effects of chlorine substituents on the aromatic rings. |
| AID1136385 | Neuroleptic activity in ip dosed Sprague-Dawley rat assessed as protection against epinephrine-induced mortality administered 1 hr prior to epinephrine injection | 1978 | Journal of medicinal chemistry, Dec, Volume: 21, Issue:12 | Neuroleptics related to butaclamol. An investigation of the effects of chlorine substituents on the aromatic rings. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.41
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.41) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||