crambescidin 816: structure given in first source; isolated from the marine sponge Crambe crambe [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Crambe | genus | [no description available] | Brassicaceae | A plant family of the order Capparales, subclass Dilleniidae, class Magnoliopsida. They are mostly herbaceous plants with peppery-flavored leaves, due to gluconapin (GLUCOSINOLATES) and its hydrolysis product butenylisotrhiocyanate. The family includes many plants of economic importance that have been extensively altered and domesticated by humans. Flowers have 4 petals. Podlike fruits contain a number of seeds. Cress is a general term used for many in the Brassicacea family. Rockcress is usually ARABIS; Bittercress is usually CARDAMINE; Yellowcress is usually RORIPPA; Pennycress is usually THLASPI; Watercress refers to NASTURTIUM; or RORIPPA or TROPAEOLUM; Gardencress refers to LEPIDIUM; Indiancress refers to TROPAEOLUM.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 164382 |
| MeSH ID | M0221324 |
| Synonym |
|---|
| crambescidin 816 |
| 135257-45-3 |
| dispiro(oxepin-2(3h),4'-(4h-5,6,8b)triazaacenaphthylene-7'(5'h),2''-(2h)pyran)-8'-carboxylic acid, 7-ethyl-1',2',2'a,3',3'',4,4'',5'',6'',7,8',8'a-dodecahydro-8'a-hydroxy-6''-methyl-, 16-((4-amino-2-hydroxybutyl)(3-aminopropyl)amino)-16-oxohexadecyl ester |
| 16-[(4-amino-2-hydroxybutyl)(3-aminopropyl)amino]-16-oxohexadecyl 7''-ethyl-2'a-hydroxy-6-methyl-1',2',2'a,3',4'',7'',8',8'a-octahydro-3''h,5'h-dispiro[oxane-2,4'-[5,6,8b]triazaacenaphthylene-7',2''-oxepine]-3'-carboxylate |
| DTXSID70928924 |
Crambescidin 816 is a guanidine alkaloid produced by the sponge Crambe crambe with known antitumoral activity.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Crambescidin 816 is a guanidine alkaloid produced by the sponge Crambe crambe with known antitumoral activity. " | ( The Marine Guanidine Alkaloid Crambescidin 816 Induces Calcium Influx and Cytotoxicity in Primary Cultures of Cortical Neurons through Glutamate Receptors. Alfonso, A; Botana, LM; Juncal, AB; Martín Vázquez, V; Mendez, AG; Silva, SBL; Thomas, OP; Vale, C; Vieytes, MR, 2017) | 2.19 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " Here, we aimed to describe the toxic activity of Cramb816 in cortical neurons." | ( The Marine Guanidine Alkaloid Crambescidin 816 Induces Calcium Influx and Cytotoxicity in Primary Cultures of Cortical Neurons through Glutamate Receptors. Alfonso, A; Botana, LM; Juncal, AB; Martín Vázquez, V; Mendez, AG; Silva, SBL; Thomas, OP; Vale, C; Vieytes, MR, 2017) | 0.74 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.13) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||