Page last updated: 2024-08-05 12:36:06

spiro compound

A compound having one atom as the only common member of two rings.

ChEBI ID: 33599

Members (6)

MemberDefinitionRole
2,2'-spirobi[3,6,7,8-tetrahydro-1H-cyclopenta[g]naphthalene]-5,5'-dioneA spiro compound that consists of two units of 1,2,3,6,7,8-hexahydro-5H-cyclopenta[b]naphthalen-5-one fused together at position 2. It is an inhibitor of Hepatitis C virus E2 protein that exhibits inhibitory activity against hepatitis C virus infections.2,2'-spirobi[3,6,7,8-tetrahydro-1H-cyclopenta[g]naphthalene]-5,5'-dione
5',7'-dimethylspiro[cyclohexane-1,3'-pyrimido[5,4-c][1,2,5]oxadiazine]-6',8'-dione5',7'-dimethylspiro[cyclohexane-1,3'-pyrimido[5,4-c][1,2,5]oxadiazine]-6',8'-dione
ainsliadimer aA sesquiterpene lactone isolated from the whole plants of Ainsliaea macrocephala; exhibits inhibitory activity against production of nitric oxide (NO).ainsliadimer A
crambescidin 800An organic heteropentacyclic guanidine alkaloid isolated from the marine sponge Crambe crambe and Batzella. It exhibits anti-HIV-1 and anti-HSV-1 activity.crambescidin 800
megestrol acetateA sesquiterpene lactone with formula C15H20O8. It is a neurotoxic natural product found in plants of the family Illiciaceae.anisatin
solavetivoneA cyclic ketone derived from spiro[4.5]dec-6-en-8-one by substitution of hydrogens by methyl groups at positions 6 and 10, and by an isopropenyl group at position 2 (the (2R,5S,10R)-diastereoisomer).solavetivone

Research

Studies (58)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19905 (8.62)18.7374
1990's5 (8.62)18.2507
2000's15 (25.86)29.6817
2010's27 (46.55)24.3611
2020's6 (10.34)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews4 (6.15%)6.00%
Case Studies2 (3.08%)4.05%
Observational0 (0.00%)0.25%
Other59 (90.77%)84.16%