Page last updated: 2024-12-08

bharangin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

bharangin: inhibits the activity of penicillinase enzyme in E coli [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID194464
CHEMBL ID1807756
MeSH IDM0166566

Synonyms (8)

Synonym
bharangin
72711-84-3
CHEMBL1807756
benzo(5,6)cyclohepta(1,2-b)pyran-2,9-dione, 3,4,11,11a-tetrahydro-10-hydroxy-4,4,11a-trimethyl-8-(1-methylethyl)-, (s)-
DTXSID00993529
10-hydroxy-4,4,11a-trimethyl-8-(propan-2-yl)-3,4,11,11a-tetrahydrobenzo[5,6]cyclohepta[1,2-b]pyran-2,9-dione
(3s)-15-hydroxy-3,7,7-trimethyl-13-propan-2-yl-4-oxatricyclo[9.4.0.03,8]pentadeca-1(15),8,10,12-tetraene-5,14-dione
AKOS040747960

Research Excerpts

Overview

Bharangin is a diterpenoid quinonemethide. It has demonstrated therapeutic potential against leukemia, lymphoma, and multiple myeloma cells.

ExcerptReferenceRelevance
"Bharangin is a diterpenoid quinonemethide that has demonstrated therapeutic potential against leukemia, lymphoma, and multiple myeloma cells."( Anti-cancer activities of Bharangin against breast cancer: Evidence for the role of NF-κB and lncRNAs.
Awasthee, N; Gupta, SC; Nair, MS; Rai, V; Sajin Francis, K; Verma, SS, 2018
)
1.5
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID608688Cytotoxicity against human A549 cells after 48 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Aug-01, Volume: 21, Issue:15
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea.
AID608689Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Aug-01, Volume: 21, Issue:15
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea.
AID608691Cytotoxicity against human HeLa cells after 48 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Aug-01, Volume: 21, Issue:15
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea.
AID608687Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Aug-01, Volume: 21, Issue:15
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea.
AID608690Cytotoxicity against human PC3 cells after 48 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Aug-01, Volume: 21, Issue:15
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.52

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.52 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.46 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.52)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]