4,4'-Diaminodibenzyl (DADB) is a diamine compound with the chemical formula C14H16N2. It is a colorless solid that is soluble in organic solvents. DADB is synthesized through the reduction of 4,4'-dinitrodibenzyl, which can be obtained through the nitration of dibenzyl. DADB has been investigated for its potential applications in various fields, including: polymers, pharmaceuticals, and electronics. It has shown promising properties as a curing agent for epoxy resins, a precursor for the synthesis of polyamides, and a component in the development of organic semiconductors. Research into DADB focuses on exploring its reactivity, its ability to form complexes with metal ions, its potential as a building block for functional materials, and its use in the development of new technologies.'
4,4'-diaminodibenzyl: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
ID Source | ID |
---|---|
PubMed CID | 12138 |
CHEMBL ID | 1704183 |
SCHEMBL ID | 187043 |
MeSH ID | M0097228 |
Synonym |
---|
smr000476340 |
MLS001180989 |
4,4'-ethylenebis(aniline) |
aniline, p,p'-ethylenedi- |
brn 0394999 |
nsc 44062 |
nsc 60033 |
nsc 580 |
einecs 210-716-7 |
aniline, 4,4'-ethylenedi- |
alpha,alpha'-bi-p-toluidine |
4,4'-diaminodibenzyl |
ccris 1004 |
BB 0221264 |
benzenamine, 4,4'-(1,2-ethanediyl)bis- |
nsc-44062 |
nsc44062 |
nsc60033 |
nsc-60033 |
4-[2-(4-aminophenyl)ethyl]phenylamine |
AH-034/32835045 |
OPREA1_504832 |
CBDIVE_013839 |
alpha, alpha-bi-p-toluidine |
4-[2-(4-aminophenyl)ethyl]aniline |
621-95-4 |
nsc580 |
.alpha.,.alpha.'-bi-p-toluidine |
nsc-580 |
aniline,4'-ethylenedi- |
1,2-bis(4-aminophenyl)ethane |
4,4'-diaminobibenzyl |
1,2-bis(p-aminophenyl)ethane |
benzenamine,4'-(1,2-ethanediyl)bis- |
4,4'-ethylenedianiline |
4,4'-ethylenedianiline, technical, >=95% (nt) |
STL089722 |
4,4'-ethane-1,2-diyldianiline |
4,4'-diamino-1,2-diphenylethane |
E0346 |
AKOS000120248 |
4-(4-aminophenethyl)benzenamine |
A8596 |
4,4 inverted exclamation marka-ethylenedianiline |
HMS2804F06 |
ec 210-716-7 |
4-13-00-00401 (beilstein handbook reference) |
FT-0617109 |
SCHEMBL187043 |
DTXSID3060742 |
W-105034 |
CHEMBL1704183 |
AC-16755 |
4-[2-(4-aminophenyl)ethyl]phenylamine # |
4,4-ethylenedianiline |
mfcd00007923 |
AS-60549 |
a,a'-bi-p-toluidine |
4,4'-(ethane-1,2-diyl)dianiline |
F16584 |
EN300-18238 |
CS-0089167 |
Z256707848 |
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
USP1 protein, partial | Homo sapiens (human) | Potency | 11.2202 | 0.0316 | 37.5844 | 354.8130 | AID743255 |
DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 89.1251 | 0.0501 | 27.0736 | 89.1251 | AID588590 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
FAD-linked sulfhydryl oxidase ALR | Homo sapiens (human) | AC50 | 1.9060 | 0.0050 | 3.2126 | 22.7870 | AID493248 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 2 (28.57) | 29.6817 |
2010's | 3 (42.86) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.59) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 8 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |