| Assay ID | Title | Year | Journal | Article |
|---|
| AID626298 | Displacement of [3H]-epibatidine from alpha1betagammadelta nAChR in human TE671 cellular membranes at 5 uM after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID626248 | Displacement of [3H]-epibatidine from Aplysia californica N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID626292 | Displacement of [3H]-epibatidine from alpha4beta2 nAChR in rat cortical membranes after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID626291 | Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID487686 | Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in rat brain membrane after 3 hrs | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6
| A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein. |
| AID640096 | Displacement of [3H]epibatidine from human alpha3beta4 nAchR expressed in SH-SY5Y cells at 5 uM | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
| Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs. |
| AID626293 | Displacement of [3H]-epibatidine from alpha3beta4 nAChR in human SH-SY5Y cellular membranes after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID391583 | Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR | 2008 | Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
| Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding. |
| AID640098 | Displacement of [3H]methyllycaconitine from rat alpha7 nAchR in rat hippocampal membrane | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
| Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs. |
| AID626299 | Agonist activity at rat recombinant alpha7 nAChR expressed in GH4C1 cells by patch clamp technique | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID487687 | Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membrane after 3 hrs | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6
| A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein. |
| AID640099 | Displacement of [3H]epibatidine from human alpha4beta2 nAchR expressed in SH-EP1 cells | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
| Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs. |
| AID640100 | Displacement of [3H]epibatidine from human alpha3beta4 nAchR expressed in SH-SY5Y cells | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
| Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs. |
| AID640097 | Displacement of [3H]epibatidine from human alpha1betagammadelta nAchR expressed in TE-671 cell membrane at 5 uM | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
| Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs. |
| AID626295 | Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes at 5 uM after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID640095 | Displacement of [3H]epibatidine from human alpha4beta2 nAchR expressed in SH-EP1 cells at 5 uM | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
| Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs. |
| AID391584 | Agonist activity at human cloned wild-type alpha7 nAChR expressed in Xenopus laevis oocytes assessed as channel opening by voltage clamp electrophysiology | 2008 | Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
| Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding. |
| AID391585 | Agonist activity at human cloned alpha7 nAChR Gln117Phe mutant expressed in Xenopus laevis oocytes assessed as channel opening by voltage clamp electrophysiology | 2008 | Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
| Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding. |
| AID626300 | Agonist activity at rat recombinant alpha7 nAChR expressed in GH4C1 cells by patch clamp technique relative to control | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID626290 | Displacement of [3H]-epibatidine from Bulinus truncatus N-terminal FLAG-tagged AChBP F149L mutant expressed in HEK293 cells after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID640094 | Displacement of [3H]methyllycaconitine from rat alpha7 nAchR in rat hippocampal membrane at 5 uM | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
| Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs. |
| AID626247 | Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID626296 | Displacement of [3H]-epibatidine from alpha4beta2 nAChR in rat cortical membranes at 5 uM after 2 hrs by liquid scintillation counting | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. |
| AID977611 | Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB | 2009 | The EMBO journal, Oct-07, Volume: 28, Issue:19
| Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |