Page last updated: 2024-10-06

TP53 Regulates Metabolic Genes

Proteins (42)

ProteinSynonymsTaxonomy
14-3-3 protein etaProtein AS1Homo sapiens (human)
Glutaminase liver isoform, mitochondrialGLS; EC 3.5.1.2; L-glutaminase; L-glutamine amidohydrolaseHomo sapiens (human)
Cellular tumor antigen p53Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53Homo sapiens (human)
Cytochrome c oxidase subunit 1EC 7.1.1.9; Cytochrome c oxidase polypeptide IHomo sapiens (human)
Cytochrome c oxidase subunit 2EC 7.1.1.9; Cytochrome c oxidase polypeptide IIHomo sapiens (human)
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Autocrine motility factor; AMF; Neuroleukin; NLK; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Sperm antigen 36; SA-36Homo sapiens (human)
14-3-3 protein theta14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1Homo sapiens (human)
Peroxiredoxin-1EC 1.11.1.24; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; Thioredoxin-dependent peroxiredoxin 1Homo sapiens (human)
Cytochrome c oxidase subunit NDUFA4Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunitHomo sapiens (human)
14-3-3 protein sigmaEpithelial cell marker protein 1; StratifinHomo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologHomo sapiens (human)
Cytochrome cHomo sapiens (human)
Glutaminase kidney isoform, mitochondrialGLS; EC 3.5.1.2; K-glutaminase; L-glutamine amidohydrolaseHomo sapiens (human)
ThioredoxinTrx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASPHomo sapiens (human)
Glucose-6-phosphate 1-dehydrogenaseG6PD; EC 1.1.1.49Homo sapiens (human)
14-3-3 protein gammaProtein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Thioredoxin reductase 1, cytoplasmicTR; EC 1.8.1.9; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1Homo sapiens (human)
14-3-3 protein beta/alphaProtein 1054; Protein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Tumor protein 63p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51Homo sapiens (human)
14-3-3 protein epsilon14-3-3EHomo sapiens (human)
GTP-binding protein RhebRas homolog enriched in brainHomo sapiens (human)
Ribonucleoside-diphosphate reductase subunit M2 BEC 1.17.4.1; TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2Homo sapiens (human)
14-3-3 protein zeta/deltaProtein kinase C inhibitor protein 1; KCIP-1Homo sapiens (human)
Fructose-2,6-bisphosphatase TIGAREC 3.1.3.46; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphataseHomo sapiens (human)
Cytochrome c oxidase subunit 7A-related protein, mitochondrialCOX7a-related protein; Cytochrome c oxidase subunit VIIa-related protein; EB1Homo sapiens (human)
Cytochrome c oxidase subunit 6A1, mitochondrialCytochrome c oxidase polypeptide VIa-liver; Cytochrome c oxidase subunit VIA-liver; COX VIa-LHomo sapiens (human)
Cytochrome c oxidase subunit 5A, mitochondrialCytochrome c oxidase polypeptide VaHomo sapiens (human)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrialCytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1Homo sapiens (human)
Protein SCO2 homolog, mitochondrialHomo sapiens (human)
Cytochrome c oxidase subunit 3EC 7.1.1.9; Cytochrome c oxidase polypeptide IIIHomo sapiens (human)
Cytochrome c oxidase subunit 6CCytochrome c oxidase polypeptide VIcHomo sapiens (human)
Cytochrome c oxidase subunit 8A, mitochondrialCytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2Homo sapiens (human)
Cytochrome c oxidase subunit 5B, mitochondrialCytochrome c oxidase polypeptide VbHomo sapiens (human)
Cytochrome c oxidase subunit 6B1Cytochrome c oxidase subunit VIb isoform 1; COX VIb-1Homo sapiens (human)
Cytochrome c oxidase subunit 7C, mitochondrialCytochrome c oxidase polypeptide VIIcHomo sapiens (human)
Cytochrome c oxidase subunit 7B, mitochondrialCytochrome c oxidase polypeptide VIIbHomo sapiens (human)
TuberinTuberous sclerosis 2 proteinHomo sapiens (human)
Cytochrome c oxidase assembly protein COX19hCOX19Homo sapiens (human)
HamartinTuberous sclerosis 1 proteinHomo sapiens (human)
Helicase MOV-10EC 3.6.4.13; Armitage homolog; Moloney leukemia virus 10 proteinHomo sapiens (human)
DNA damage-inducible transcript 4 proteinHIF-1 responsive protein RTP801; Protein regulated in development and DNA damage response 1; REDD-1Homo sapiens (human)
Glutathione peroxidase 2GPx-2; GSHPx-2; EC 1.11.1.9; Gastrointestinal glutathione peroxidase; Glutathione peroxidase-gastrointestinal; GPx-GI; GSHPx-GI; Glutathione peroxidase-related protein 2; GPRP-2Homo sapiens (human)

Compounds (21)

CompoundDescription
hydronium ion
Ammonium
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
carbon monoxideCarbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)
Orthophosphate
Glutathione DisulfideA GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Guanosine DiphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
6-phosphonoglucono-delta-lactone
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
polyglutamineRN given for (D)-isomer
fructose 2,6-diphosphatephosphofructokinase activator synthesized via Mg-ATP & fructose-6-P
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)