Compounds > emd 53998
Page last updated: 2024-09-05

emd 53998 and digoxin

emd 53998 has been researched along with digoxin in 2 studies

Compound Research Comparison

Studies
(emd 53998)		Trials
(emd 53998)		Recent Studies (post-2010)
(emd 53998)		Studies
(digoxin)		Trials
(digoxin)		Recent Studies (post-2010) (digoxin)
1120911,4839581,289

Protein Interaction Comparison

ProteinTaxonomyemd 53998 (IC50)digoxin (IC50)
STAT3, partialHomo sapiens (human)1.862
Sodium/potassium-transporting ATPase subunit alpha-1 Homo sapiens (human)0.32
Sodium/potassium-transporting ATPase subunit beta-1Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit alpha-3 Rattus norvegicus (Norway rat)0.22
Sodium/potassium-transporting ATPase subunit beta-1 Rattus norvegicus (Norway rat)0.0055
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.19
Sodium/potassium-transporting ATPase subunit alpha-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit beta-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-2Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-1Canis lupus familiaris (dog)0.5
Nuclear receptor ROR-gammaHomo sapiens (human)3.4798
Sodium/potassium-transporting ATPase subunit beta-3Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit gammaHomo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Homo sapiens (human)0.335
Sodium/potassium-transporting ATPase subunit alpha-4Rattus norvegicus (Norway rat)0.0055
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)3.2359

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abe, Y; Ishisu, R; Nakano, T; Onishi, K; Sekioka, K1
Allessie, M; Blaauw, Y; de Haan, S; Greiser, M; Harks, E; Schotten, U; van Hunnik, A; Verheule, S1

Other Studies

2 other study(ies) available for emd 53998 and digoxin

ArticleYear
Differential effects of EMD-53998 on calcium-pressure relationship in normal and ischemic guinea pig heart.
    The American journal of physiology, 1996, Volume: 271, Issue:1 Pt 2

    Topics: Animals; Blood Pressure; Calcium; Cardiotonic Agents; Digoxin; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardium; Quinolines; Reference Values; Thiadiazines; Ventricular Function, Left

1996
AVE0118, blocker of the transient outward current (I(to)) and ultrarapid delayed rectifier current (I(Kur)), fully restores atrial contractility after cardioversion of atrial fibrillation in the goat.
    Circulation, 2006, Sep-19, Volume: 114, Issue:12

    Topics: Action Potentials; Animals; Atrial Fibrillation; Atrial Function, Right; Biphenyl Compounds; Cardiotonic Agents; Delayed Rectifier Potassium Channels; Digoxin; Dihydropyridines; Disease Models, Animal; Dobutamine; Electric Countershock; Electrocardiography; Goats; Myocardial Contraction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Quinolines; Thiadiazines

2006