Compounds > desmethylastemizole
Page last updated: 2024-09-04

desmethylastemizole and droperidol

desmethylastemizole has been researched along with droperidol in 3 studies

Compound Research Comparison

Studies
(desmethylastemizole)		Trials
(desmethylastemizole)		Recent Studies (post-2010)
(desmethylastemizole)		Studies
(droperidol)		Trials
(droperidol)		Recent Studies (post-2010) (droperidol)
12122,065500181

Protein Interaction Comparison

ProteinTaxonomydesmethylastemizole (IC50)droperidol (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)7.6
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.454
Bile salt export pumpHomo sapiens (human)10
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.849
Muscarinic acetylcholine receptor M5Homo sapiens (human)2.298
Alpha-2A adrenergic receptorHomo sapiens (human)2.965
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.9272
D(2) dopamine receptorHomo sapiens (human)0.0024
Alpha-2B adrenergic receptorHomo sapiens (human)0.22
Alpha-2C adrenergic receptorHomo sapiens (human)1.763
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.242
D(1A) dopamine receptorHomo sapiens (human)1.092
Alpha-1D adrenergic receptorHomo sapiens (human)0.083
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0026
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.454
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.242
Histamine H1 receptorHomo sapiens (human)4.519
D(3) dopamine receptorHomo sapiens (human)0.0028
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.342
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)7.6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.1318
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)7.6
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)7.6
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.9272

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L1
Jia, L; Sun, H1

Other Studies

3 other study(ies) available for desmethylastemizole and droperidol

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008