Compounds > cyc 202
Page last updated: 2024-09-04

cyc 202 and harmine

cyc 202 has been researched along with harmine in 5 studies

Compound Research Comparison

Studies
(cyc 202)		Trials
(cyc 202)		Recent Studies (post-2010)
(cyc 202)		Studies
(harmine)		Trials
(harmine)		Recent Studies (post-2010) (harmine)
97973931,00111400

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)harmine (IC50)
Chain A, Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.35
Glycogen synthase kinase-3 beta Sus scrofa (pig)10
[Tau protein] kinase Sus scrofa (pig)10
Dual specificity protein kinase CLK2Mus musculus (house mouse)0.28
Dual specificity protein kinase CLK4Mus musculus (house mouse)0.05
Dual specificity tyrosine-phosphorylation-regulated kinase 3Homo sapiens (human)0.604
Cyclin-T1Homo sapiens (human)0.72
Cyclin-A2Homo sapiens (human)10
Amine oxidase [flavin-containing] AHomo sapiens (human)0.0044
Dual specificity protein kinase CLK1Mus musculus (house mouse)0.072
Cyclin-dependent kinase 2Homo sapiens (human)10
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.072
Casein kinase I isoform deltaHomo sapiens (human)1.5
Casein kinase I isoform epsilonHomo sapiens (human)1.5
Dual specificity protein kinase CLK1Homo sapiens (human)0.086
Cyclin-dependent kinase 9Homo sapiens (human)0.72
Cyclin-dependent-like kinase 5 Homo sapiens (human)8
Aldehyde oxidaseHomo sapiens (human)0.03
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.0917
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)8
Dual specificity tyrosine-phosphorylation-regulated kinase 1ARattus norvegicus (Norway rat)0.0397
Serine/threonine-protein kinase pim-3Homo sapiens (human)4.3
Serine/threonine-protein kinase haspinHomo sapiens (human)0.59
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)1.3137
Dual specificity tyrosine-phosphorylation-regulated kinase 4Homo sapiens (human)9.5
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)5.08
Dual specificity tyrosine-phosphorylation-regulated kinase 1BHomo sapiens (human)0.1183

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deng, Y; Duan, J; Kesuma, D; Qi, RZ; Sim, MM; Song, Y; Teng, SF; Wang, J; Wang, JH1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Babault, L; Baratte, B; Bazureau, JP; Carreaux, F; Debdab, M; Eisenreich, A; Fedorov, O; Filippakopoulos, P; Hagiwara, M; Knapp, S; Lozach, O; Meijer, L; Ogawa, Y; Rauch, U; Renault, S; Soundararajan, M; Tahtouh, T1
Bui, LC; Cariou, K; Dairou, J; Delabar, JM; Denhez, C; Dodd, RH; Gourdain, S; Janel, N; Rodrigues-Lima, F1
Jarhad, DB; Jeong, LS; Kim, HR; Mashelkar, KK; Noh, M1

Reviews

1 review(s) available for cyc 202 and harmine

ArticleYear
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics.
    Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22

    Topics: Animals; Biological Products; Disease; Dyrk Kinases; Enzyme Activation; Humans; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases

2018

Other Studies

4 other study(ies) available for cyc 202 and harmine

ArticleYear
Beta-carbolines as specific inhibitors of cyclin-dependent kinases.
    Bioorganic & medicinal chemistry letters, 2002, Apr-08, Volume: 12, Issue:7

    Topics: Carbolines; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Protein Serine-Threonine Kinases

2002
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
    Journal of medicinal chemistry, 2011, Jun-23, Volume: 54, Issue:12

    Topics: Alternative Splicing; Animals; Aquatic Organisms; Benzodioxoles; Crystallography, X-Ray; Cyclin-Dependent Kinases; Dyrk Kinases; Endothelial Cells; Humans; Imidazolines; Microvessels; Models, Molecular; Nuclear Proteins; Phosphorylation; Porifera; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quantitative Structure-Activity Relationship; RNA Precursors; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Stereoisomerism

2011
Development of DANDYs, new 3,5-diaryl-7-azaindoles demonstrating potent DYRK1A kinase inhibitory activity.
    Journal of medicinal chemistry, 2013, Dec-12, Volume: 56, Issue:23

    Topics: Dyrk Kinases; Enzyme Inhibitors; Humans; Hydrogen Bonding; Indoles; KB Cells; Molecular Docking Simulation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines

2013