biotin has been researched along with orlistat in 3 studies
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (orlistat) | Trials (orlistat) | Recent Studies (post-2010) (orlistat) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 1,432 | 274 | 539 |
| Protein | Taxonomy | biotin (IC50) | orlistat (IC50) |
|---|---|---|---|
| Phosphatidylserine lipase ABHD16A | Homo sapiens (human) | 0.1 | |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | 0.4214 | |
| Lipoprotein lipase | Homo sapiens (human) | 0.066 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.42 | |
| Hepatic triacylglycerol lipase | Homo sapiens (human) | 0.003 | |
| Pancreatic triacylglycerol lipase | Homo sapiens (human) | 0.3253 | |
| Translocator protein | Rattus norvegicus (Norway rat) | 1 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.42 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.1903 | |
| Fatty acid synthase | Homo sapiens (human) | 2.99 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 0.01 | |
| Platelet-activating factor acetylhydrolase | Homo sapiens (human) | 0.05 | |
| Diacylglycerol lipase-alpha | Mus musculus (house mouse) | 0.02 | |
| Lysophosphatidylserine lipase ABHD12 | Homo sapiens (human) | 0.1682 | |
| Diacylglycerol lipase-beta | Homo sapiens (human) | 0.24 | |
| Monoacylglycerol lipase ABHD6 | Homo sapiens (human) | 0.03 | |
| Acyl-protein thioesterase 2 | Rattus norvegicus (Norway rat) | 0.17 | |
| Diacylglycerol lipase-alpha | Homo sapiens (human) | 0.2677 | |
| Endothelial lipase | Homo sapiens (human) | 0.006 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Axelrod, F; Browne, CD; Knowles, LM; Smith, JW | 1 |
| Blankman, JL; Cravatt, BF; Simon, GM | 1 |
3 other study(ies) available for biotin and orlistat
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A fatty acid synthase blockade induces tumor cell-cycle arrest by down-regulating Skp2.
Topics: Avidin; Biotin; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Fatty Acid Synthases; Fatty Acids; G1 Phase; Humans; Lactones; Lipase; Obesity; Orlistat; Palmitic Acid; Retinoblastoma Protein; RNA, Small Interfering; S Phase; S-Phase Kinase-Associated Proteins; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligases | 2004 |
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol.
Topics: Animals; Arachidonic Acids; Benzamides; Biotin; Brain; Carbamates; Catalysis; Chlorocebus aethiops; COS Cells; Endocannabinoids; Enzyme Inhibitors; Glycerides; Hydrolases; Lactones; Membrane Proteins; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Organophosphorus Compounds; Orlistat; Proteomics; Subcellular Fractions; Transfection | 2007 |