aj 76 and apomorphine
aj 76 has been researched along with apomorphine in 8 studies
Compound Research Comparison
| Studies (aj 76) | Trials (aj 76) | Recent Studies (post-2010) (aj 76) | Studies (apomorphine) | Trials (apomorphine) | Recent Studies (post-2010) (apomorphine) |
|---|---|---|---|---|---|
| 37 | 0 | 2 | 9,205 | 287 | 780 |
Protein Interaction Comparison
| Protein | Taxonomy | aj 76 (IC50) | apomorphine (IC50) |
|---|---|---|---|
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | 0.22 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0146 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D | Rattus norvegicus (Norway rat) | 0.4744 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.3385 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.025 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.025 | |
| D(1B) dopamine receptor | Homo sapiens (human) | 0.025 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.063 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.1432 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.025 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.75 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0813 | |
| E3 ubiquitin-protein ligase Mdm2 | Homo sapiens (human) | 0.205 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 1.35 | |
| D | Bos taurus (cattle) | 0.3385 |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Andrieux, M; Besançon, R; Giros, B; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P | 1 |
| Bouthenet, ML; Giros, B; Martres, MP; Schwartz, JC; Sokoloff, P | 1 |
| Arvidsson, LE; Carlsson, A; Hacksell, U; Johansson, AM; Nilsson, JL; Svensson, K | 1 |
| Carlsson, A; Hansson, L; Lin, CH; Smith, MW; Sonesson, C; Svensson, K; Waters, N; Wikström, H | 1 |
| Lum, JT; Piercey, MF | 1 |
| Dourish, CT; Herbert, EN; Iversen, SD | 1 |
| Carlsson, A; Johansson, AM; Magnusson, T; Svensson, K | 1 |
| Carlsson, A; Hajos, M; Hjorth, S; Svensson, K | 1 |
Other Studies
8 other study(ies) available for aj 76 and apomorphine
| Article | Year |
|---|---|
Pharmacology of human dopamine D3 receptor expressed in a mammalian cell line: comparison with D2 receptor.
Topics: Animals; Chlorides; CHO Cells; Cricetinae; Dopamine; Dopamine Agents; Dopamine Antagonists; Guanylyl Imidodiphosphate; Humans; Lithium; Lithium Chloride; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Sodium Chloride; Sulpiride; Transfection | 1992 |
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
Topics: Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line; Cloning, Molecular; Cricetinae; DNA; DNA Restriction Enzymes; Dopamine; Guanylyl Imidodiphosphate; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Sequence Homology, Nucleic Acid; Tissue Distribution | 1990 |
Resolved cis- and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists.
Topics: Animals; Behavior, Animal; Body Temperature; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Synergism; Limbic System; Male; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Structure-Activity Relationship; Tetrahydronaphthalenes | 1987 |
Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships.
Topics: Animals; Benzazepines; Brain; CHO Cells; Cricetinae; Dihydroxyphenylalanine; Dopamine D2 Receptor Antagonists; Habituation, Psychophysiologic; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Structure; Motor Activity; Optical Rotation; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; Reserpine; Serotonin Antagonists; Spiperone; Structure-Activity Relationship; Transfection | 1994 |
Electrophysiological effects of dopamine autoreceptor antagonists, (+)-AJ 76 and (+)-UH 232.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Apomorphine; Dendrites; Dopamine; Dopamine Antagonists; Electrophysiology; Feedback; Haloperidol; In Vitro Techniques; Male; Naphthalenes; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra; Tetrahydronaphthalenes | 1990 |
Blockade of apomorphine-induced yawning in rats by the dopamine autoreceptor antagonist (+)-AJ 76.
Topics: Animals; Apomorphine; Behavior, Animal; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes; Yawning | 1989 |
(+)-AJ 76 and (+)-UH 232: central stimulants acting as preferential dopamine autoreceptor antagonists.
Topics: 4-Butyrolactone; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Brain; Male; Methyltyrosines; Motor Activity; Naphthalenes; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Tetrahydronaphthalenes | 1986 |
In vivo dopamine (DA) receptor binding and behavioural effects of the putative DA autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 in rats with a unilateral nigral 6-OH-DA lesion.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Functional Laterality; Hydroxydopamines; Male; Naphthalenes; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Tetrahydronaphthalenes | 1988 |