S 23121: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
flumipropyn : A racemate comprising equimolar amounts of (R)- and (S)-flumipropynflumipropyn. A protoporphyrinogen oxidase inhibitor introduced by the Sumitomo Chemical Co., it was formerly used for the control of grasses and broad-leaved weeds in various crops. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
2-[5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione : A dicarboximide that is 4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione in which the nitrogen has been substituted by a 5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 158434 |
| CHEMBL ID | 2287110 |
| CHEBI ID | 139040 |
| CHEBI ID | 5105 |
| SCHEMBL ID | 38980 |
| MeSH ID | M0222027 |
| Synonym |
|---|
| flumipropyn |
| 84478-52-4 |
| C10993 , |
| s-23121 |
| CHEBI:139040 |
| 2-[5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl]-4,5,6,7-tetrahydro-1h-isoindole-1,3(2h)-dione |
| 2-(5-but-3-yn-2-yloxy-4-chloro-2-fluorophenyl)-4,5,6,7-tetrahydroisoindole-1,3-dione |
| AC1L4JX1 , |
| y3e93z8tul , |
| s 23121 |
| 1h-isoindole-1,3(2h)-dione, 2-(4-chloro-2-fluoro-5-((1-methyl-2-propynyl)oxy)phenyl)-4,5,6,7-tetrahydro- |
| n-(4-chloro-2-fluoro-5-((1-methyl-2-propynyl)oxy)phenyl)-3,4,5,6-tetrahydrophthalimide |
| flumipropyn [iso:bsi] |
| unii-y3e93z8tul |
| chebi:5105 |
| CHEMBL2287110 |
| SCHEMBL38980 |
| DTXSID90868818 |
| 2-{5-[(but-3-yn-2-yl)oxy]-4-chloro-2-fluorophenyl}-4,5,6,7-tetrahydro-1h-isoindole-1,3(2h)-dione |
| Q27106661 |
| flumipropyn [iso] |
| 2-(4-chloro-2-fluoro-5-((1-methyl-2-propyn-1-yl)oxy)phenyl)-4,5,6,7-tetrahydro-1h-isoindole-1,3(2h)-dione |
| 1h-isoindole-1,3(2h)-dione, 2-(4-chloro-2-fluoro-5-((1-methyl-2-propyn-1-yl)oxy)phenyl)-4,5,6,7-tetrahydro- |
| 2-(5-but-3-yn-2-yloxy-4-chloro-2-fluoro-phenyl)-4,5,6,7-tetrahydroisoindole-1,3-dione |
| Excerpt | Reference | Relevance |
|---|---|---|
| "S-53482, 7-fluoro-6-[(3,4,5,6-tetrahydro)phthalimido]-4-(2-propynyl)-1,4-benzoxazin-3(2H)-one (flumioxazin), is an N-phenylimide herbicide and developmentally toxic to rats, but not to rabbits." | ( Close link between protoporphyrin IX accumulation and developmental toxicity induced by N-phenylimide herbicides in rats. Fantel, AG; Kato, T; Kawamura, S, 2014) | 0.4 |
| "The developmentally toxic compounds caused PPIX accumulation in embryos." | ( Close link between protoporphyrin IX accumulation and developmental toxicity induced by N-phenylimide herbicides in rats. Fantel, AG; Kato, T; Kawamura, S, 2014) | 0.4 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " The same faecal metabolites as those detected in faeces of the rat dosed with 14C-labelled S-23121 were similarly found after dosing with any of the 35S-labelled chemicals." | ( Metabolism of N-[4-chloro-2-fluoro-5-[(1-methyl-2- propynl)oxy]phenyl]-3,4,5,6-tetrahydrophthalimide (S-23121) in the rat: I. Identification of a new, sulphonic acid type of conjugate. Kaneko, H; Matsunaga, H; Nakatsuka, I; Yamada, H; Yoshino, H; Yoshitake, A, 1993) | 0.29 |
| Class | Description |
|---|---|
| dicarboximide | An imide in which the two acyl substituents on nitrogen are carboacyl groups. |
| terminal acetylenic compound | An acetylenic compound which a carbon of the C#C moiety is attached to a hydrogen atom. |
| aromatic ether | Any ether in which the oxygen is attached to at least one aryl substituent. |
| monofluorobenzenes | Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying a single fluorine substitutent. |
| monochlorobenzenes | Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine. |
| pyrroline | Any organic heteromonocyclic compound with a structure based on a dihydropyrrole. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.53) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||