proximadiol: dicyclic sesquiterpenediol from Cymbopogon proximus with antispasmodic activity [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Cymbopogon | genus | A plant genus of the family POACEAE which is a source of citronella oil and lemongrass oil.[MeSH] | Poaceae | A large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.[MeSH] |
| Cymbopogon proximus | species | [no description available] | Poaceae | A large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 165258 |
| CHEMBL ID | 465860 |
| CHEBI ID | 67796 |
| SCHEMBL ID | 6512725 |
| MeSH ID | M0057129 |
| Synonym |
|---|
| proximadiol |
| C17676 |
| cryptomeridiol |
| 4666-84-6 |
| (1r,4ar,7r,8ar)-7-(2-hydroxypropan-2-yl)-1,4a-dimethyldecahydronaphthalen-1-ol |
| eudesmane-4alpha,11-diol |
| CHEMBL465860 |
| chebi:67796 , |
| (1r,4ar,7r,8ar)-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,5,6,7,8,8a-octahydronaphthalen-1-ol |
| y2kbv9fz9m , |
| unii-y2kbv9fz9m |
| 2-naphthalenemethanol, decahydro-8-hydroxy-alpha,alpha,4a,8-tetramethyl-, (2r-(2alpha,4aalpha,8beta,8abeta))- |
| (1r,4ar,7r,8ar)-7-(1-hydroxy-1-methyl-ethyl)-1,4a-dimethyl-decalin-1-ol |
| LKKDASYGWYYFIK-QHSBEEBCSA-N |
| 2-naphthalenemethanol, decahydro-8-hydroxy-.alpha.,.alpha.,4a,8-tetramethyl-, [2r-(2.alpha.,4a.alpha.,8..beta.,8a.beta.)]- |
| SCHEMBL6512725 |
| (1r,4ar,7r,8ar)-7-(2-hydroxy-2-propanyl)-1,4a-dimethyldecahydro-1-naphthalenol |
| 5.beta.,7.beta.h,10.alpha.-eudesmane-4,11-diol |
| 2-naphthalenemethanol, 1,2.beta.,3,4,4a,5,6,7,8,8a.beta.-decahydro-8.beta.-hydroxy-.alpha.,.alpha.,4a.alpha.,8-tetramethyl- |
| selina-4,7-diol |
| 2-naphthalenemethanol, decahydro-8-hydroxy-.alpha.,.alpha.,4a,8-tetramethyl-, (2r-(2.alpha.,4a.alpha.,8.beta.,8a.beta.))- |
| 2-naphthalenemethanol, decahydro-8-hydroxy-.alpha.,.alpha.,4a,8-tetramethyl-, (2r,4ar,8r,8ar)- |
| j13.424d , |
| (2r,8r,8a.beta.)-decahydro-8-hydroxy-.alpha.,.alpha.,4a.alpha.,8-tetramethyl-2-naphthalenemethanol |
| selinane-4.alpha.,11-diol |
| kryptomeridiol |
| (2r,8r,8abeta)-decahydro-8-hydroxy-alpha,alpha,4aalpha,8-tetramethyl-2-naphthalenemethanol |
| 2-naphthalenemethanol, decahydro-8-hydroxy-alpha,alpha,4a,8-tetramethyl-, (2r,4ar,8r,8ar)- |
| 2-naphthalenemethanol, 1,2beta,3,4,4a,5,6,7,8,8abeta-decahydro-8beta-hydroxy-alpha,alpha,4aalpha,8-tetramethyl- |
| 5beta,7betah,10alpha-eudesmane-4,11-diol |
| selinane-4alpha,11-diol |
| AKOS032948473 |
| Q27136273 |
| FS-9904 |
| 2-naphthalenemethanol, 1,2,3,4,4a,5,6,7,8,8a-decahydro-8-hydroxy-,,4a,8-tetramethyl-;proximadiol; selina-4,7-diol; selinane-4,11-diol |
| DTXSID001317282 |
| Role | Description |
|---|---|
| metabolite | Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| eudesmane sesquiterpenoid | Any sesquiterpenoid having a eudesmane skeleton. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID361439 | Cytotoxicity against human HT-29 cells by MTT assay | 2002 | Journal of natural products, Nov, Volume: 65, Issue:11 | Cytotoxic diarylheptanoids from the roots of Juglans mandshurica. |
| AID361440 | Cytotoxicity against human A549 cells by MTT assay | 2002 | Journal of natural products, Nov, Volume: 65, Issue:11 | Cytotoxic diarylheptanoids from the roots of Juglans mandshurica. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (33.29) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||