Page last updated: 2024-12-08
nooglutil
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
nooglutil: RN refers to (L)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 147523 |
| SCHEMBL ID | 2497750 |
| MeSH ID | M0181978 |
Synonyms (22)
| Synonym |
|---|
| brn 4200454 |
| n-5-(hydroxynicotinoyl)-l-glutamic acid |
| l-glutamic acid, n-((5-hydroxy-3-pyridinyl)carbonyl)- |
| onk-10 |
| nooglutil |
| (2s)-2-[(5-hydroxypyridine-3-carbonyl)amino]pentanedioic acid |
| unii-09um5jos3w |
| 112193-35-8 |
| 09um5jos3w , |
| AKOS013164096 |
| n-5-(hydroxynicotinoyl)-l-glutamic acid [who-dd] |
| onk10 |
| nooglutyl |
| (2s)-2-((5-hydroxypyridine-3-carbonyl)amino)pentanedioic acid |
| SCHEMBL2497750 |
| n-(5-oxynicotinoyl)-l-glutamic acid |
| n-(5-hydroxynicotinoyl)-l-glutamic acid |
| DTXSID90920687 |
| (5-hydroxynicotinoyl)-l-glutamic acid |
| XFZGYOJFPGPYCS-QMMMGPOBSA-N |
| Q15425767 |
| (2s)-2-[(5-hydroxypyridin-3-yl)formamido]pentanedioic acid |
Research Excerpts
Pharmacokinetics
| Excerpt | Reference | Relevance |
|---|---|---|
| " The ONG concentration decay had a two-phase character in both rats and rabbits, so that the pharmacokinetic profiles were fitted to a biexponential equation of the two-compartment model." | ( [Pharmacokinetics of n-(5-oxynicotinoyl)-L-glutamic acid calcium salt upon bolus administration in rats and rabbits: interspecies extrapolation]. Dolgova, GV; Dovzhenko, SA; Firsov, AA; Kiselev, AV; Kobrin, MB; Pomerantseva, TIa; Portnoĭ, IuA; Stovbun, SV, 2010) | 0.36 |
Bioavailability
| Excerpt | Reference | Relevance |
|---|---|---|
| "Comparative study of the main pharmacokinetic characteristics and evaluation of the bioavailability of two experimental tablet forms of the new nootropic nooglutil in relation to the substance of the drug were conducted on rabbits." | ( [The bioavailability of tableted drug forms of the new Russian nootropic preparation nooglutil in rabbits]. Chesnokova, EA; Kartashov, VS; Sariev, AK; Smirnov, LD; Zherdev, VP, ) | 0.55 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 23.17
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (23.17) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 15 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||