n-butoxy-2-propanol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

n-butoxy-2-propanol: structure & RN given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	21210
CHEMBL ID	1903014
SCHEMBL ID	15902
MeSH ID	M0173135

Synonyms (46)

Synonym
1,2-propylene glycol 1-monobutyl ether
2-hydroxy-3-butoxypropane
1-butoxy-2-propanol
n-butoxypropanol
wln: qy1&1o4
5131-66-8
nsc2211
nsc-2211
2-propanol, 1-butoxy-
propasol solvent b
ai3-18549
propylene glycol n-butyl ether
brn 1733910
n-butoxy-2-propanol
nsc 2211
einecs 225-878-4
propanol, 1(or 2)-butoxy-
NCGC00163821-02
NCGC00163821-01
1-butoxypropan-2-ol
propylene glycol 1-monobutyl ether
B0864
inchi=1/c7h16o2/c1-3-4-5-9-6-7(2)8/h7-8h,3-6h2,1-2h3
rwnusvwfhdhrcj-uhfffaoysa-
NCGC00163821-03
AKOS009158796
dtxsid8027589 ,
tox21_200680
dtxcid707589
NCGC00258234-01
cas-5131-66-8
propyleneglycol butyl ether
ec 225-878-4
unii-k0mr13cz2e
k0mr13cz2e ,
FT-0607557
SCHEMBL15902
propylene glycol 1-butyl ether
solvenon pnb
1-methyl-3-oxa-1-heptanol
CHEMBL1903014
mfcd00021904
Q24762634
CS-0199145
EN300-7086325
F71173

Research Excerpts

Dosage Studied

Excerpt	Relevance	Reference
" The dosage volume was 2 ml/kg."	( Determination of the developmental toxicity potential of butoxypropanol in rabbits after topical administration. Christian, MS; Gibson, WB; Nolen, GA, 1989)	0.28

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (6)

Potency Measurements

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
GLI family zinc finger 3	Homo sapiens (human)	Potency	31.2308	0.0007	14.5928	83.7951	AID1259369
glucocorticoid receptor [Homo sapiens]	Homo sapiens (human)	Potency	177.8280	0.0002	14.3764	60.0339	AID588532
retinoid X nuclear receptor alpha	Homo sapiens (human)	Potency	501.1870	0.0008	17.5051	59.3239	AID588544
pregnane X nuclear receptor	Homo sapiens (human)	Potency	398.1070	0.0054	28.0263	1,258.9301	AID720659
vitamin D (1,25- dihydroxyvitamin D3) receptor	Homo sapiens (human)	Potency	284.4397	0.0237	23.2282	63.5986	AID588541; AID588543; AID743223
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	363.1377	0.0006	27.2152	1,122.0200	AID651741; AID743219
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (16.67)	18.7374
1990's	1 (16.67)	18.2507
2000's	3 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (16.67)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.72 (24.57)
Research Supply Index	1.95 (2.92)
Research Growth Index	4.66 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.72)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
formaldehyde paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy	3.35	2	aldehyde; one-carbon compound	allergen; carcinogenic agent; disinfectant; EC 3.5.1.4 (amidase) inhibitor; environmental contaminant; Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
propylene glycol methyl ether propylene glycol methyl ether: RN given refers to unspecified methoxypropanol; structure	2.49	2
n-butoxyethanol n-butoxyethanol: RN given refers to parent cpd; structure. 2-butoxyethanol : A primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group. A high-boiling (171degreeC) colourless liquid, it is used as a solvent for paints and inks, as well as in some dry cleaning solutions.	3.61	3	glycol ether; primary alcohol	protic solvent
butyl carbitol butyl carbitol: structure	1.97	1	ether

Condition	Relationship Strength	Studies
Leucocythaemia [description not available]	2.94	1
Cancer of Nasopharynx [description not available]	2.94	1
Leukemia A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)	2.94	1
Nasopharyngeal Neoplasms Tumors or cancer of the NASOPHARYNX.	2.94	1
Benign Neoplasms [description not available]	2.03	1
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	2.03	1
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	1.97	1
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	1.97	1

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