Compounds > n-butoxy-2-propanol
Page last updated: 2024-12-06

n-butoxy-2-propanol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

n-butoxy-2-propanol: structure & RN given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID21210
CHEMBL ID1903014
SCHEMBL ID15902
MeSH IDM0173135

Synonyms (46)

Synonym
1,2-propylene glycol 1-monobutyl ether
2-hydroxy-3-butoxypropane
1-butoxy-2-propanol
n-butoxypropanol
wln: qy1&1o4
5131-66-8
nsc2211
nsc-2211
2-propanol, 1-butoxy-
propasol solvent b
ai3-18549
propylene glycol n-butyl ether
brn 1733910
n-butoxy-2-propanol
nsc 2211
einecs 225-878-4
propanol, 1(or 2)-butoxy-
NCGC00163821-02
NCGC00163821-01
1-butoxypropan-2-ol
propylene glycol 1-monobutyl ether
B0864
inchi=1/c7h16o2/c1-3-4-5-9-6-7(2)8/h7-8h,3-6h2,1-2h3
rwnusvwfhdhrcj-uhfffaoysa-
NCGC00163821-03
AKOS009158796
dtxsid8027589 ,
tox21_200680
dtxcid707589
NCGC00258234-01
cas-5131-66-8
propyleneglycol butyl ether
ec 225-878-4
unii-k0mr13cz2e
k0mr13cz2e ,
FT-0607557
SCHEMBL15902
propylene glycol 1-butyl ether
solvenon pnb
1-methyl-3-oxa-1-heptanol
CHEMBL1903014
mfcd00021904
Q24762634
CS-0199145
EN300-7086325
F71173

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" The dosage volume was 2 ml/kg."( Determination of the developmental toxicity potential of butoxypropanol in rabbits after topical administration.
Christian, MS; Gibson, WB; Nolen, GA, 1989)		0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (6)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
GLI family zinc finger 3Homo sapiens (human)Potency31.23080.000714.592883.7951AID1259369
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency177.82800.000214.376460.0339AID588532
retinoid X nuclear receptor alphaHomo sapiens (human)Potency501.18700.000817.505159.3239AID588544
pregnane X nuclear receptorHomo sapiens (human)Potency398.10700.005428.02631,258.9301AID720659
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency284.43970.023723.228263.5986AID588541; AID588543; AID743223
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency363.13770.000627.21521,122.0200AID651741; AID743219
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.72 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.72)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
formaldehyde
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy		3.3520aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
propylene glycol methyl ether
propylene glycol methyl ether: RN given refers to unspecified methoxypropanol; structure		2.4920
n-butoxyethanol
n-butoxyethanol: RN given refers to parent cpd; structure. 2-butoxyethanol : A primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group. A high-boiling (171degreeC) colourless liquid, it is used as a solvent for paints and inks, as well as in some dry cleaning solutions.		3.6130glycol ether;
primary alcohol		protic solvent
butyl carbitol
butyl carbitol: structure		1.9710ether
ConditionIndicatedRelationship StrengthStudiesTrials
Leucocythaemia
[description not available]		02.9410
Cancer of Nasopharynx
[description not available]		02.9410
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)		02.9410
Nasopharyngeal Neoplasms
Tumors or cancer of the NASOPHARYNX.		02.9410
Benign Neoplasms
[description not available]		02.0310
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.0310
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.		01.9710
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		01.9710