| Assay ID | Title | Year | Journal | Article |
|---|
| AID243826 | Inhibitory activity against beta-secretase 1 (BACE1) at 2 uM | 2005 | Bioorganic & medicinal chemistry letters, Jan-03, Volume: 15, Issue:1
| Design and synthesis of highly active Alzheimer's beta-secretase (BACE1) inhibitors, KMI-420 and KMI-429, with enhanced chemical stability. |
| AID317230 | Inhibition of human recombinant BACE1 at 0.2 uM | 2008 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 18, Issue:5
| BACE1 inhibitors: optimization by replacing the P1' residue with non-acidic moiety. |
| AID314585 | Inhibition of human recombinant BACE1 by FRET assay | 2008 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 18, Issue:5
| Novel non-peptidic and small-sized BACE1 inhibitors. |
| AID241188 | Inhibitory activity against beta-secretase 1 (BACE1) | 2005 | Bioorganic & medicinal chemistry letters, Jan-03, Volume: 15, Issue:1
| Design and synthesis of highly active Alzheimer's beta-secretase (BACE1) inhibitors, KMI-420 and KMI-429, with enhanced chemical stability. |
| AID614067 | Inhibition of BACE1 | 2011 | Bioorganic & medicinal chemistry, Sep-01, Volume: 19, Issue:17
| Structure-guided design and synthesis of P1' position 1-phenylcycloalkylamine-derived pentapeptidic BACE1 inhibitors. |
| AID268731 | Inhibition of human recombinant BACE1 at 0.2 uM | 2006 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 16, Issue:16
| beta-Secretase inhibitors: modification at the P4 position and improvement of inhibitory activity in cultured cells. |
| AID243835 | Inhibitory activity against beta-secretase 1 (BACE1) at 0.2 uM | 2005 | Bioorganic & medicinal chemistry letters, Jan-03, Volume: 15, Issue:1
| Design and synthesis of highly active Alzheimer's beta-secretase (BACE1) inhibitors, KMI-420 and KMI-429, with enhanced chemical stability. |
| AID550164 | Inhibition of BACE1 | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors. |
| AID317229 | Inhibition of human recombinant BACE1 at 2 uM | 2008 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 18, Issue:5
| BACE1 inhibitors: optimization by replacing the P1' residue with non-acidic moiety. |
| AID264166 | Inhibition of BACE1 | 2006 | Bioorganic & medicinal chemistry letters, May-01, Volume: 16, Issue:9
| Design and synthesis of potent beta-secretase (BACE1) inhibitors with P1' carboxylic acid bioisosteres. |
| AID264164 | Inhibition of BACE1 at 2 uM | 2006 | Bioorganic & medicinal chemistry letters, May-01, Volume: 16, Issue:9
| Design and synthesis of potent beta-secretase (BACE1) inhibitors with P1' carboxylic acid bioisosteres. |
| AID640217 | Inhibition of human recombinant BACE1 by FRET assay | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2
| Tripeptidic BACE1 inhibitors devised by in-silico conformational structure-based design. |
| AID317231 | Inhibition of BACE1 | 2008 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 18, Issue:5
| BACE1 inhibitors: optimization by replacing the P1' residue with non-acidic moiety. |
| AID268730 | Inhibition of human recombinant BACE1 at 2 uM | 2006 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 16, Issue:16
| beta-Secretase inhibitors: modification at the P4 position and improvement of inhibitory activity in cultured cells. |
| AID264165 | Inhibition of BACE1 at 0.2 uM | 2006 | Bioorganic & medicinal chemistry letters, May-01, Volume: 16, Issue:9
| Design and synthesis of potent beta-secretase (BACE1) inhibitors with P1' carboxylic acid bioisosteres. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |