Page last updated: 2024-11-13

jiadifenolide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

jiadifenolide: from Illicium jiadifengpi; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
IlliciumgenusA plant genus of the family SCHISANDRACEAE, order AUSTROBAILEYALES, class MAGNOLIOPSIDA. They have evergreen, aromatic leaves and bisexual flowers. The female portion of the flower consists of 7 to 15 carpels.[MeSH]SchisandraceaeA plant family of the order AUSTROBAILEYALES, class MAGNOLIOPSIDA.[MeSH]

Cross-References

ID SourceID
PubMed CID44542225
MeSH IDM0542562

Synonyms (3)

Synonym
(-)-jiadifenolide
jiadifenolide
Q21099634

Research Excerpts

Effects

ExcerptReferenceRelevance
"Jiadifenolide has been reported to have neurotrophin-like activity in primary rat cortical neurons, and also possesses neurotrophic effects in neuronal precursor cells derived from human induced pluripotent stem cells (hiPSCs), as we have previously reported. "( Jiadifenolide induces the expression of cellular communication network factor (CCN) genes, and CCN2 exhibits neurotrophic activity in neuronal precursor cells derived from human induced pluripotent stem cells.
Aoyama, E; Fukuyama, Y; Harada, K; Kubo, M; Kuzuhara, T; Minato, H; Nishioka, M; Seki, M; Shoji, M; Suzuki, Y; Takigawa, M; Ueda, M, 2019
)
3.4
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's12 (92.31)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.50 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index5.84 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (22.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (7.69%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (92.31%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]