Compounds > irtemazole
Page last updated: 2024-11-06

irtemazole

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Description

irtemazole: MF C18-H16-N4 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID71330
CHEMBL ID2105112
SCHEMBL ID636285
MeSH IDM0168962

Synonyms (41)

Synonym
irtemazolum
irtemazol
irtemazole [usan:inn:ban]
aak27wy74i ,
unii-aak27wy74i
1h-benzimidazole, 5-(1h-imidazol-1-ylphenylmethyl)-2-methyl-, (+-)-
(+-)-5-(alpha-imidazol-1-ylbenzyl)-2-methylbenzimidazole
irtemazolum [inn-latin]
r 60844
irtemazol [inn-spanish]
irtemazole
r-60844
D04617
irtemazole (usan/inn)
115574-30-6
6-[imidazol-1-yl(phenyl)methyl]-2-methyl-1h-benzimidazole
r60844
CHEMBL2105112
SCHEMBL636285
1h-benzimidazole, 5-(1h-imidazol-1-ylphenylmethyl)-2-methyl-, (+/-)-
irtemazole [usan]
irtemazole [inn]
(+/-)-5-(.alpha.-imidazol-1-ylbenzyl)-2-methylbenzimidazole
1h-benzimidazole, 5-(1h-imidazol-1-ylphenylmethyl)-2-methyl-
1h-benzimidazole, 6-(1h-imidazol-1-ylphenylmethyl)-2-methyl-
AKOS030530803
129369-64-8
unii-zpe7cm7fng
unii-bz8gv6sk6h
5-((1h-imidazol-1-yl)(phenyl)methyl)-2-methyl-1h-benzo[d]imidazole
irtemazole, (-)-
115576-85-7
1h-benzimidazole, 5-(1h-imidazol-1-ylphenylmethyl)-2-methyl-, (+)-
1h-benzimidazole, 5-(1h-imidazol-1-ylphenylmethyl)-2-methyl-, (-)-
ZPE7CM7FNG ,
irtemazole, (+)-
115576-86-8
BZ8GV6SK6H ,
Q27273833
DTXSID80869596
6-[(1h-imidazol-1-yl)(phenyl)methyl]-2-methyl-1h-benzimidazole
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (14.29%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
uric acid
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.. uric acid : An oxopurine that is the final oxidation product of purine metabolism.. 6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.. 7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.		3.0750uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
xanthine
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.. 9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.		1.9710xanthineSaccharomyces cerevisiae metabolite
benzbromarone
Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.. benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.		1.97101-benzofurans;
aromatic ketone		uricosuric drug
hypoxanthine
[no description available]		1.9710nucleobase analogue;
oxopurine;
purine nucleobase		fundamental metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Gouty Arthritis
[description not available]		01.9710
Gout
Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.		01.9710
Arthritis, Gouty
Arthritis, especially of the great toe, as a result of gout. Acute gouty arthritis often is precipitated by trauma, infection, surgery, etc. The initial attacks are usually monoarticular but later attacks are often polyarticular. Acute and chronic gouty arthritis are associated with accumulation of MONOSODIUM URATE in and around affected joints.		01.9710