Page last updated: 2024-12-07

glg-v 13

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

GLG-V 13: a class III antiarrhythmic agent; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9828688
MeSH IDM0250541

Synonyms (2)

Synonym
glg-v 13
3,7-diazabicyclo[3.3.1]nonane, 3-[4-(1h-imidazol-1-yl)benzoyl]-7-(1-methylethyl)-, diperchlorate

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"The acute and subchronic toxic effects of GLG-V-13 (3-[4-(1H-imidazol-1-yl)benzoyl]-7-isopropyl-3,7-diazabicyclo[3."( Preliminary acute and subchronic toxicity studies of GLG-V-13, a novel class III antiarrhythmic agent, in mice.
Berlin, KD; Chandra, SA; Chen, CL; Chen, H; Cowell, RL; Garrison, GL; Kim, S; Lazzara, R; Qualls, CW; Roder, JD; Sangiah, S; Scherlag, BJ, 2000
)
0.31

Bioavailability

ExcerptReferenceRelevance
" Oral bioavailability was estimated to be 53."( Pharmacokinetics and plasma protein binding of the new potent class III antiarrhythmic agent 3-[4-(1H-imidazol-1-yl)benzoyl]-7-isopropyl-3, 7-diazabicyclo[3.3.1]nonane dihydroperchlorate.
Berlin, KD; Chen, CL; Chen, H; Garrison, GL; Lazzara, R; Roder, JD; Sangiah, S; Scherlag, BJ, 1995
)
0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]