Page last updated: 2024-11-13
galphimine e
Description
galphimine E: isolated from the Mexican plant Galphimia glauca; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Flora | Rank | Flora Definition | Family | Family Definition |
Galphimia | genus | A plant genus of the family MALPIGHIACEAE. G. glauca is the source of 'Galphimia glauca extract' and contains 'galphimine B' and tetragalloylquinic acid.[MeSH] | Malpighiaceae | A plant family of the order Polygalales, subclass Rosidae class, Magnoliopsida that are mostly shrubs and small trees. Many of the members contain indole alkaloids.[MeSH] |
Cross-References
Synonyms (3)
Synonym |
galphimine e |
CHEMBL502176 |
methyl (1s,2r,5s,10s,11s,14s,15s,21r,22r,23s)-22-acetyloxy-10,23-dihydroxy-21-[(1r)-1-hydroxyethyl]-2,5,8,14-tetramethyl-18-oxo-19-oxapentacyclo[12.9.0.02,11.05,10.015,21]tricosa-7,16-diene-11-carboxylate |
Research Excerpts
Pharmacokinetics
Bioassays (4)
Assay ID | Title | Year | Journal | Article |
AID401223 | Cytotoxicity against human SQC1 cells | 2004 | Journal of natural products, Apr, Volume: 67, Issue:4
| Isolation of nor-secofriedelanes from the sedative extracts of Galphimia glauca. |
AID401221 | Cytotoxicity against human HCT15 cells | 2004 | Journal of natural products, Apr, Volume: 67, Issue:4
| Isolation of nor-secofriedelanes from the sedative extracts of Galphimia glauca. |
AID401222 | Cytotoxicity against human OVCAR cells | 2004 | Journal of natural products, Apr, Volume: 67, Issue:4
| Isolation of nor-secofriedelanes from the sedative extracts of Galphimia glauca. |
AID401220 | Cytotoxicity against human KB cells | 2004 | Journal of natural products, Apr, Volume: 67, Issue:4
| Isolation of nor-secofriedelanes from the sedative extracts of Galphimia glauca. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (7)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (57.14) | 29.6817 |
2010's | 2 (28.57) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.36
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.36 (24.57) | Research Supply Index | 2.08 (2.92) | Research Growth Index | 4.44 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 7 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |