Page last updated: 2024-11-12
fuscol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
fuscol: isolated from the shallow water octocoral Eunicea fusca; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 10891538 |
CHEMBL ID | 476288 |
MeSH ID | M000603878 |
Synonyms (3)
Synonym |
---|
fuscol |
CHEMBL476288 |
(3e,5e)-6-[(1s,3r,4r)-4-ethenyl-4-methyl-3-prop-1-en-2-ylcyclohexyl]-2-methylhepta-3,5-dien-2-ol |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (11)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID621753 | Antiinflammatory activity in mouse assessed as inhibition of TPA-induced mouse ear edema at 0.5 mg/ear administered relative to untreated control | 2011 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 21, Issue:19 | Fuscoside E: a strong anti-inflammatory diterpene from Caribbean octocoral Eunicea fusca. |
AID400412 | Antifungal activity against Cladosporium cucumerinum at 0.2 umol after 2 days | 1998 | Journal of natural products, Mar, Volume: 61, Issue:3 | Four new bioactive lobane diterpenes of the soft coral Lobophytum pauciflorum from Mindoro, Philippines. |
AID1165102 | Antiinflammatory activity in mouse assessed as reduction in PMA-induced ear edema at 0.1 mg/ear administered topically measured after 24 hrs relative to control | 2014 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 24, Issue:20 | Synthesis and evaluation of anti-inflammatory activity of derivatives of the marine natural products fuscol and eunicol. |
AID636132 | Cytotoxicity against human A431 cells after 4 days by coulter counting | 2012 | Bioorganic & medicinal chemistry, Jan-15, Volume: 20, Issue:2 | Cyclolobatriene, a novel prenylated germacrene diterpene, from the soft coral Lobophytum pauciflorum. |
AID400414 | Toxicity in Artemia salina after 48 hrs | 1998 | Journal of natural products, Mar, Volume: 61, Issue:3 | Four new bioactive lobane diterpenes of the soft coral Lobophytum pauciflorum from Mindoro, Philippines. |
AID400411 | Antifungal activity against Cladosporium cucumerinum at 0.4 umol after 2 days | 1998 | Journal of natural products, Mar, Volume: 61, Issue:3 | Four new bioactive lobane diterpenes of the soft coral Lobophytum pauciflorum from Mindoro, Philippines. |
AID678054 | Antiinflammatory activity in CD1 mouse ear edema model assessed as reduction in phorbol myristate acetate-induced edema at 0.1 mg/ear administered topically at right ear 1 hr before phorbol myristate acetate challenge and measured 24 hrs post dose | 2012 | Journal of natural products, Jul-27, Volume: 75, Issue:7 | Eunicidiol, an anti-inflammatory dilophol diterpene from Eunicea fusca. |
AID678056 | Toxicity in CD1 mouse model phorbol myristate acetate-induced ear edema model at 0.1 mg/ear administered topically at right ear 1 hr before phorbol myristate acetate challenge and measured 24 hrs post dose | 2012 | Journal of natural products, Jul-27, Volume: 75, Issue:7 | Eunicidiol, an anti-inflammatory dilophol diterpene from Eunicea fusca. |
AID1165103 | Toxicity in mouse at 0.1 mg/ear administered topically | 2014 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 24, Issue:20 | Synthesis and evaluation of anti-inflammatory activity of derivatives of the marine natural products fuscol and eunicol. |
AID400413 | Antifungal activity against Cladosporium cucumerinum at 0.1 umol after 2 days | 1998 | Journal of natural products, Mar, Volume: 61, Issue:3 | Four new bioactive lobane diterpenes of the soft coral Lobophytum pauciflorum from Mindoro, Philippines. |
AID400410 | Antifungal activity against Cladosporium cucumerinum at 0.8 umol after 2 days | 1998 | Journal of natural products, Mar, Volume: 61, Issue:3 | Four new bioactive lobane diterpenes of the soft coral Lobophytum pauciflorum from Mindoro, Philippines. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (80.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 21.83
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (21.83) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |