Compounds > deoxyfusapyrone

Page last updated: 2024-11-13

deoxyfusapyrone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

deoxyfusapyrone: isolated from Fusarium semitectum; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	54684866
CHEMBL ID	593901
MeSH ID	M0233983

Synonyms (10)

Synonym
CHEMBL593901
deoxyneofusapyrone
deoxyfusapyrone
156856-32-5
3-[(2s,3r,4s,6s)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-4-hydroxy-6-[(4e,6e,9z)-3-hydroxy-2,6,8,10,12-pentamethyloctadeca-4,6,9-trien-2-yl]pyran-2-one
rel-3-((2s,3r,4s,6s)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)-2-hydroxy-6-((4e,6e,9z)-3-hydroxy-2,6,8,10,12-pentamethyloctadeca-4,6,9-trien-2-yl)-4h-pyran-4-one
3-[(2s,3r,4s,6s)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-2-hydroxy-6-[(4e,6e,9z)-3-hydroxy-2,6,8,10,12-pentamethyloctadeca-4,6,9-trien-2-yl]pyran-4-one
HY-N10273
CS-0372134
AKOS040756228

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (16)

Assay ID	Title	Year	Journal	Article
AID1103189	Antifungal activity against Rhodotorula glutinis assessed as growth inhibition at 50 ug/ml after 24 to 72 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID1103190	Antifungal activity against Meyerozyma guilliermondii assessed as growth inhibition at 50 ug/ml after 24 to 72 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID453159	Cytotoxicity against human HepG2 cells	2010	Bioorganic & medicinal chemistry letters, Jan-15, Volume: 20, Issue:2	Novel neofusapyrones isolated from Verticillium dahliae as potent antifungal substances.
AID1103192	Antifungal activity against Penicillium brevicompactum Dierckx ITEM-449 after 72 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID1103196	Antifungal activity against Aspergillus parasiticus Speare ITEM-11 after 48 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID1103198	Antifungal activity against Botryotinia fuckeliana ITEM-966 after 72 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID453156	Antifungal activity against Cochliobolus miyabeanus at 100 ng/ml	2010	Bioorganic & medicinal chemistry letters, Jan-15, Volume: 20, Issue:2	Novel neofusapyrones isolated from Verticillium dahliae as potent antifungal substances.
AID453158	Cytotoxicity against human HeLa cells	2010	Bioorganic & medicinal chemistry letters, Jan-15, Volume: 20, Issue:2	Novel neofusapyrones isolated from Verticillium dahliae as potent antifungal substances.
AID1103193	Antifungal activity against Penicillium brevicompactum Dierckx ITEM-449 after 48 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID1103199	Antifungal activity against Botryotinia fuckeliana ITEM-966 after 48 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID1103191	Toxicity against Artemia salina (brine shrimp) larvae after 24 hr	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID453157	Antibacterial activity against methicillin-resistant Staphylococcus aureus Isolate 87-7927 at 10 ug	2010	Bioorganic & medicinal chemistry letters, Jan-15, Volume: 20, Issue:2	Novel neofusapyrones isolated from Verticillium dahliae as potent antifungal substances.
AID1103197	Antifungal activity against Aspergillus parasiticus Speare ITEM-11 after 24 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID1103200	Antifungal activity against Botryotinia fuckeliana ITEM-966 after 24 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID1103194	Antifungal activity against Penicillium brevicompactum Dierckx ITEM-449 after 24 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
AID1103195	Antifungal activity against Aspergillus parasiticus Speare ITEM-11 after 72 hr by broth dilution method	2004	Journal of agricultural and food chemistry, May-19, Volume: 52, Issue:10	Structure-activity relationships of derivatives of fusapyrone, an antifungal metabolite of Fusarium semitectum.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (28.57)	18.2507
2000's	4 (57.14)	29.6817
2010's	1 (14.29)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
dicloran 2,6-dichloro-4-nitroaniline : A nitroaniline that is 4-nitroaniline in which the hydrogens at positions 2 and 6 are replaced by chlorines. An agricultural fungicide, it is not approved for use in the European Union.	2.02	1	0	aromatic fungicide; dichlorobenzene; nitroaniline	antifungal agrochemical
benomyl [no description available]	2.02	1	0	aromatic amide; benzimidazole fungicide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	acaricide; anthelminthic drug; antifungal agrochemical; microtubule-destabilising agent; tubulin modulator
alkenes [no description available]	2.01	1	0
glucose, (beta-d)-isomer beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages.	2.05	1	0	D-glucopyranose	epitope; mouse metabolite
nystatin a1 Nystatin: Macrolide antifungal antibiotic complex produced by Streptomyces noursei, S. aureus, and other Streptomyces species. The biologically active components of the complex are nystatin A1, A2, and A3.. nystatin : A heterogeneous mixture of polyene compounds produced by cultures of Streptomyces noursei. It mainly consists of three biologically active components designated nystatin A1, nystatin A2, and nystatin A3. It is used to treat oral and dermal fungal infections.. nystatin A1 : A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species.	2	1	0	nystatins
fusapyrone fusapyrone: isolated from Fusarium semitectum; structure in first source	2.92	4	0