Compounds > ck 0569 a
Page last updated: 2024-12-06

ck 0569 a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

guanidino propyl piperazine: anti-plaque agent; RN given refers to dimethanesulfonate; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID50288
MeSH IDM0087236

Synonyms (26)

Synonym
ipexidine mesylate
D04602
69017-90-9
ipexidine mesylate (usan)
urea, n,n'-(1,4-piperazinediylbis(3,1-propanediyliminocarbonimidoyl)bis(n'-hexyl-, dimethanesulfonate
urea, n,n''-(1,4-piperazinediylbis(3,1-propanediyliminocarbonimidoyl)bis(n'-hexyl-, dimethanesulfonate
ci8ct0864p ,
cko 569a
1,4-bis(3-(n-hexylcarbamylguanidino)propyl)piperazine dimethanesulfonic acid
ck 0569 a
ck-0569 [as the base]
1,1'-(1,4-piperazinediylbis(trimethyleneiminoimidocarbonyl))bis(3-hexylurea) dimethanesulfonate
ipexidine mesylate [usan:inn]
unii-ci8ct0864p
guanidino propyl piperazine
ipexidine mesilate
ck-0569a
ck-569a
urea, n,n''-(1,4-piperazinediylbis(3,1-propanediyliminocarbonimidoyl)bis(n'-hexyl-, dimethanesulphonate
ck-0569 mesylate
ipexidine mesylate [usan]
1,1'-(1,4-piperazinediylbis(trimethyleneiminoimidocarbonyl))bis(3-hexylurea) dimethanesulphonate
methanesulfonic acid--n,n''-{piperazine-1,4-diylbis[(propane-3,1-diyl)carbamimidoyl]}bis(n'-hexylcarbamimidic acid) (2/1)
DTXSID80988771
Q27275478
1-[n'-[3-[4-[3-[[amino-(hexylcarbamoylamino)methylidene]amino]propyl]piperazin-1-yl]propyl]carbamimidoyl]-3-hexylurea;methanesulfonic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (20.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
urea
pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.		1.9610isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
guanidine
Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.. guanidine : An aminocarboxamidine, the parent compound of the guanidines.		1.9610carboxamidine;
guanidines;
one-carbon compound
guanidine carboxamide
guanidine carboxamide: RN given refers to parent cpd		1.9610organooxygen compound
adamantane
Adamantane: A tricyclo bridged hydrocarbon.		1.9610adamantanes;
polycyclic alkane
octenidine
[no description available]		1.9610dihydropyridine
chlorhexidine
Chlorhexidine: A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.. chlorhexidine : A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge.		4.0431biguanides;
monochlorobenzenes		antibacterial agent;
antiinfective agent
ConditionIndicatedRelationship StrengthStudiesTrials
Dental Plaque
A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.		04.2641
Tooth Discoloration
Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)		01.9610
Gingivitis
Inflammation of gum tissue (GINGIVA) without loss of connective tissue.		02.3620
Caries, Dental
[description not available]		01.9610
Dental Caries
Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.		01.9610