BE 10988: from a strain of actinomycetes; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 126200 |
| CHEMBL ID | 8740 |
| SCHEMBL ID | 13342863 |
| MeSH ID | M0189982 |
| Synonym |
|---|
| be 10988 |
| CHEMBL8740 |
| 2-(5-amino-1-methyl-4,7-dioxoindol-3-yl)-1,3-thiazole-4-carboxamide |
| 4-thiazolecarboxamide, 2-(5-amino-4,7-dihydro-1-methyl-4,7-dioxo-1h-indol-3-yl)- |
| be-10988 |
| unii-9b0ryt97p7 |
| 9b0ryt97p7 , |
| 135261-89-1 |
| SCHEMBL13342863 |
| DTXSID90159293 |
| antibiotic be 10988 |
| 2-(5-amino-4,7-dihydro-1-methyl-4,7-dioxo-1h-indol-3-yl)-4-thiazolecarboxamide |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID213603 | The IC50 value was measured on V79 cells in the presence of nitrogen using MTT assay. | 1995 | Journal of medicinal chemistry, Mar-17, Volume: 38, Issue:6 | Synthesis and biological activity of thiazolylindolequinones, analogues of the natural product BE 10988. |
| AID232611 | Ratio of IC50 against V79 cells in the presence of air to that of nitrogen. | 1995 | Journal of medicinal chemistry, Mar-17, Volume: 38, Issue:6 | Synthesis and biological activity of thiazolylindolequinones, analogues of the natural product BE 10988. |
| AID201633 | The IC50 value was measured on human breast cancer cell line SK-BR-3. | 1995 | Journal of medicinal chemistry, Mar-17, Volume: 38, Issue:6 | Synthesis and biological activity of thiazolylindolequinones, analogues of the natural product BE 10988. |
| AID213602 | The IC50 value was measured on V79 cells in the presence of air using MTT assay. | 1995 | Journal of medicinal chemistry, Mar-17, Volume: 38, Issue:6 | Synthesis and biological activity of thiazolylindolequinones, analogues of the natural product BE 10988. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.42) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (20.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 4 (80.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||