Page last updated: 2024-12-07

bacimethrin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID96318
SCHEMBL ID459540
MeSH IDM0153539

Synonyms (25)

Synonym
brn 0610202
nsc 66577
3690-12-8
bacimetrin
nsc-66577
nsc66577
4-amino-5-hydroxymethyl-2-methoxypyrimidine
4-amino-2-methoxy-5-pyrimidinemethanol
BACIMETHRIN ,
2-methoxy-4-amino-5-hydroxymethylpyrimidine
bacimethrine
5-pyrimidinemethanol, 4-amino-2-methoxy-
(4-amino-2-methoxypyrimidin-5-yl)methanol
AKOS006276206
378z7n5rel ,
unii-378z7n5rel
5-25-13-00322 (beilstein handbook reference)
bacimethrin [mi]
4-amino-5-(hydroxymethyl)-2-methoxypyrimidine
SCHEMBL459540
DTXSID70190381
BS-16688
Q27256660
D83536
SB57694

Research Excerpts

Overview

Bacimethrin is an analog of the 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) moiety of thiamine. It inhibits the growth of Salmonella enterica serovar Typhimurium.

ExcerptReferenceRelevance
"Bacimethrin is an analog of the 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) moiety of thiamine and inhibits the growth of Salmonella enterica serovar Typhimurium on a defined medium. "( Action of the thiamine antagonist bacimethrin on thiamine biosynthesis.
Croal, LR; Downs, DM; Zilles, JL, 2000
)
2.03

Actions

ExcerptReferenceRelevance
"Bacimethrin does not cause repression of the genes coding for the thiamin biosynthetic enzymes."( The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite.
Begley, TP; Lee, J; Melnick, JS; Perkins, J; Reddick, JJ; Saha, S, 2001
)
1.33
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pathways (1)

PathwayProteinsCompounds
bacimethrin and bacimethrin pyrophosphate biosynthesis414

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (28.57)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.14

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.14 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.14)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]