Page last updated: 2024-12-07
bacimethrin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 96318 |
| SCHEMBL ID | 459540 |
| MeSH ID | M0153539 |
Synonyms (25)
| Synonym |
|---|
| brn 0610202 |
| nsc 66577 |
| 3690-12-8 |
| bacimetrin |
| nsc-66577 |
| nsc66577 |
| 4-amino-5-hydroxymethyl-2-methoxypyrimidine |
| 4-amino-2-methoxy-5-pyrimidinemethanol |
| BACIMETHRIN , |
| 2-methoxy-4-amino-5-hydroxymethylpyrimidine |
| bacimethrine |
| 5-pyrimidinemethanol, 4-amino-2-methoxy- |
| (4-amino-2-methoxypyrimidin-5-yl)methanol |
| AKOS006276206 |
| 378z7n5rel , |
| unii-378z7n5rel |
| 5-25-13-00322 (beilstein handbook reference) |
| bacimethrin [mi] |
| 4-amino-5-(hydroxymethyl)-2-methoxypyrimidine |
| SCHEMBL459540 |
| DTXSID70190381 |
| BS-16688 |
| Q27256660 |
| D83536 |
| SB57694 |
Research Excerpts
Overview
Bacimethrin is an analog of the 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) moiety of thiamine. It inhibits the growth of Salmonella enterica serovar Typhimurium.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Bacimethrin is an analog of the 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) moiety of thiamine and inhibits the growth of Salmonella enterica serovar Typhimurium on a defined medium. " | ( Action of the thiamine antagonist bacimethrin on thiamine biosynthesis. Croal, LR; Downs, DM; Zilles, JL, 2000) | 2.03 |
Actions
| Excerpt | Reference | Relevance |
|---|---|---|
| "Bacimethrin does not cause repression of the genes coding for the thiamin biosynthetic enzymes." | ( The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite. Begley, TP; Lee, J; Melnick, JS; Perkins, J; Reddick, JJ; Saha, S, 2001) | 1.33 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Pathways (1)
| Pathway | Proteins | Compounds |
|---|---|---|
| bacimethrin and bacimethrin pyrophosphate biosynthesis | 4 | 14 |
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 20.14
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (20.14) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||