Page last updated: 2024-12-07
aschantin
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
aschantin: from flower buds of Magnolia fargesii; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Related Flora
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Magnolia | genus | A plant genus of the family MAGNOLIACEAE. The germacranolide sesquiterpene lactones costunolide, parthenolide, and costunolide diepoxide have been isolated from the leaves. Bark contains honokiol and magnolol. Parts are an ingredient of Banxia Houpo Tang.[MeSH] | Magnoliaceae | A plant family of the order Magnoliales, subclass Magnoliidae, class Magnoliopsida. They are trees and shrubs having an elongated conelike floral axis with fragrant flowers that have six tepals (sepals and petals that are not distinctly different) and many spirally arranged stamens.[MeSH] |
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 122643 |
| SCHEMBL ID | 17969446 |
| MeSH ID | M0547583 |
Synonyms (15)
| Synonym |
|---|
| ACON1_000607 |
| (+)-aschantin |
| 13060-15-6 |
| 5-[(3s,3ar,6s,6ar)-6-(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-1,3-benzodioxole |
| 1,3-benzodioxole, 5-[tetrahydro-4-(3,4,5-trimethoxyphenyl)-1h,3h-furo[3,4-c]furan-1-yl]-, (1s,3ar,4s,6ar)- |
| aschantin |
| MEGXP0_000713 |
| NCGC00168917-01 |
| BRD-K09922030-001-01-3 |
| C17845 |
| 1,3-benzodioxole, 5-(tetrahydro-4-(3,4,5-(trimethoxyphenyl)-1h,3h-furo(3,4-c)furan-1-yl))-, (1s-(1alpha,3aalpha,4alpha,6aalpha))- |
| 5-(tetrahydro-4-(3,4,5-(trimethoxyphenyl)-1h,3h-furo(3,4-c)furan-1-yl))-1,3-benzodioxole (1s-(1alpha,3aalpha,4alpha,6aalpha))- |
| DTXSID00156632 |
| SCHEMBL17969446 |
| AKOS040736022 |
Research Excerpts
Overview
Aschantin is a bioactive neolignan found in Magnolia flos. It has antiplasmodial, Ca(2+)-antagonistic, platelet activating factor-antagonism, and chemopreventive activities.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Aschantin is a bioactive neolignan found in Magnolia flos with antiplasmodial, Ca(2+)-antagonistic, platelet activating factor-antagonistic, and chemopreventive activities. " | ( Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes. Cho, YY; Jeong, HU; Kim, JH; Kwon, SS; Lee, HS; Oh, SR, 2016) | 2.19 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 20.91
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (20.91) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||