Compounds > aminobenzyl-edta
Page last updated: 2024-11-07

aminobenzyl-edta

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

aminobenzyl-EDTA: RN given refers to cpd without isomeric designation; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID134715
CHEMBL ID81013
SCHEMBL ID1742184
MeSH IDM0161280

Synonyms (16)

Synonym
CHEMBL81013
glycine, n,n'-(1-((4-aminophenyl)methyl)-1,2-ethanediyl)bis(n-(carboxymethyl)-
aminobenzyl-edta
84256-90-6
2,2',2'',2'''-{[3-(4-aminophenyl)propane-1,2-diyl]dinitrilo}tetraacetic acid
2-[[3-(4-aminophenyl)-2-[bis(carboxymethyl)amino]propyl]-(carboxymethyl)amino]acetic acid
FT-0648726
AKOS015889513
SCHEMBL1742184
RPBJIOJIMOUOIN-UHFFFAOYSA-N
1-(p-aminobenzyl)ethylenediaminetetraacetic acid
1-(4-aminobenzyl)ethylenediamine-n,n,n',n'-tetraacetic acid
aminobenzyl-edta, >=90% (chn)
2,2',2'',2'''-(3-(4-aminophenyl)propane-1,2-diyl)bis(azanetriyl)tetraacetic acid
DTXSID301004541
2-{[1-(4-aminophenyl)-3-[bis(carboxymethyl)amino]propan-2-yl](carboxymethyl)amino}acetic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (7)

Assay IDTitleYearJournalArticle
AID26719Biodistribution of labeled B72.3-chelator conjugate(EDTA isothiocynates) in Nude mice bearing LS174T tumors, in spleen, administered intravenously expressed as % of injected dose of indium-111 per gram of tissue1989Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
Synthesis of novel bifunctional chelators and their use in preparing monoclonal antibody conjugates for tumor targeting.
AID26718Biodistribution of labeled B72.3-chelator conjugate(EDTA isothiocynates) in Nude mice bearing LS174T tumors, in lungs, administered intravenously expressed as % of injected dose of indium-111 per gram of tissue1989Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
Synthesis of novel bifunctional chelators and their use in preparing monoclonal antibody conjugates for tumor targeting.
AID26504Biodistribution of labeled B72.3-chelator conjugate (EDTA isothiocynates) in Nude mice bearing LS174T tumor (Ag-), administered intravenously; ND is no data.1989Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
Synthesis of novel bifunctional chelators and their use in preparing monoclonal antibody conjugates for tumor targeting.
AID26505Biodistribution of labeled B72.3-chelator conjugate (EDTA isothiocynates) in Nude mice bearing LS174T tumors, in blood, administered intravenously expressed as % of injected dose of indium-111 per gram of tissue1989Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
Synthesis of novel bifunctional chelators and their use in preparing monoclonal antibody conjugates for tumor targeting.
AID26721Biodistribution of labeled B72.3-chelator conjugatec in Nude mice bearing LS174T tumor (Ag+), administered intravenously expressed as % of injected dose of indium-111 per gram of tissue1989Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
Synthesis of novel bifunctional chelators and their use in preparing monoclonal antibody conjugates for tumor targeting.
AID26720Biodistribution of labeled B72.3-chelator conjugate(EDTA isothiocynates) in nude mice bearing LS174T tumors, in kidney, administered intravenously expressed as % of injected dose of indium-111 per gram of tissue1989Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
Synthesis of novel bifunctional chelators and their use in preparing monoclonal antibody conjugates for tumor targeting.
AID26717Biodistribution of labeled B72.3-chelator conjugate(EDTA isothiocynates) in Nude mice bearing LS174T tumors, in liver, administered intravenously expressed as % of injected dose of indium-111 per gram of tissue1989Journal of medicinal chemistry, Jan, Volume: 32, Issue:1
Synthesis of novel bifunctional chelators and their use in preparing monoclonal antibody conjugates for tumor targeting.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.51

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.51 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.51)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
pentetic acid
Pentetic Acid: An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.		2.3720pentacarboxylic acidcopper chelator
edetic acid
Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.		2.9340ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
ethylenediamine-n,n'-bis(2-hydroxyphenylacetic acid)
ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid): synthetic iron chelator; RN given refers to parent cpd; structure in 3rd source		1.9710
mercury
Mercury: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.. mercury(0) : Elemental mercury of oxidation state zero.		2.0610elemental mercury;
zinc group element atom		neurotoxin
technetium
Technetium: The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, and atomic number 43. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.		1.9710manganese group element atom
cadmium
Cadmium: An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.. elemental cadmium : An element in the zinc group of the periodic table with atomic number 48, atomic mass 112, M.P. 321degreeC, and B.P. 765degreeC). An odourless, tasteless, and highly poisonous soft, ductile, lustrous metal with electropositive properties. It has eight stable isotopes: (106)Cd, (108)Cd,(110)Cd, (111)Cd, (112)Cd, (113)Cd, (114)Cd and (116)Cd, with (112)Cd and (114)Cd being the most common.		2.0810cadmium molecular entity;
zinc group element atom
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.		2.0810benzenes;
phenyl acetates
1-(4-bromoacetamidobenzyl)edta
1-(4-bromoacetamidobenzyl)EDTA: bifunctional chelating agent. (S)-1-(4-bromoacetamidobenzyl)EDTA : A tetracarboxylic acid consisting of ethylenediaminetetraacetic acid having a 4-bromoacetamidobenzyl group at the C1-position and (S)-configuration.		1.9710tetracarboxylic acidchelator
ConditionIndicatedRelationship StrengthStudiesTrials
Experimental Neoplasms
[description not available]		01.9710