| Assay ID | Title | Year | Journal | Article |
|---|
| AID772814 | Displacement of [3H]-nisoxetine from human NET expressed in HEK cell membranes | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716351 | Binding affinity to M4 muscarinic receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772775 | Inhibition of muscarinic M1 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452498 | Inhibition of D2 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772777 | Inhibition of 5-HT5A receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716581 | Binding affinity to Histamine H3 receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID716578 | Binding affinity to D5 dopamine receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452468 | Binding affinity to sigma 2 receptor | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772783 | Inhibition of histamine H4 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452493 | Inhibition of beta2 adrenoceptor receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452485 | Inhibition of 5HT receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452500 | Inhibition of Delta opioid receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716330 | Binding affinity to 5-HT1B receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID716577 | Binding affinity to D4 dopamine receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452474 | Inhibition of 5HT1B receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716350 | Binding affinity to M3 muscarinic receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452482 | Inhibition of 5HT5A receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452480 | Inhibition of 5HT3 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452502 | Inhibition of histamine H2 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452506 | Inhibition of mu opioid receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772778 | Inhibition of 5-HT6 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452504 | Inhibition of histamine H4 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716339 | Binding affinity to kappa opioid receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID716349 | Binding affinity to M2 muscarinic receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452487 | Inhibition of Alpha1B adrenoceptor receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452483 | Inhibition of 5HT6 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716354 | Binding affinity to M5 muscarinic receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772791 | Inhibition of rat brain BZP receptor by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716576 | Binding affinity to D2 dopamine receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID716580 | Binding affinity to Histamine H1 receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID716337 | Binding affinity to mu opioid receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452490 | Inhibition of Alpha2C adrenoceptor receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716575 | Binding affinity to D1 dopamine receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772771 | Inhibition of muscarinic M4 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452489 | Inhibition of Alpha2B adrenoceptor receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452471 | Binding affinity to Alpha2C adrenoceptor receptor | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452475 | Inhibition of 5HT1D receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID730796 | Displacement of [3H](+)-pentazocine from sigma-1 receptor in guinea pig brain | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6
| 3D-QSAR and docking studies of pentacycloundecylamines at the sigma-1 (σ1) receptor. |
| AID452503 | Inhibition of histamine H3 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772769 | Inhibition of kappa opioid receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452481 | Inhibition of 5HT4 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772772 | Inhibition of muscarinic M5 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452479 | Inhibition of 5HT2C receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772790 | Inhibition of dopamine D2 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452477 | Inhibition of 5HT2A receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452492 | Inhibition of beta-1 adrenoceptor receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452507 | Inhibition of NET at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716345 | Binding affinity to 5-HT7 receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID716569 | Binding affinity to D3 dopamine receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772796 | Inhibition of adrenergic alpha1A receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716346 | Binding affinity to M1 muscarinic receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID716582 | Binding affinity to 5-HT2B receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772803 | Neuroprotective activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide release up to 100 uM after 20 to 24 hrs by Griess assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716327 | Binding affinity to Histamine H2 receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452469 | Binding affinity to DAT | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452486 | Inhibition of Alpha1A adrenoceptor receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716589 | Binding affinity to alpha2A adrenergic receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772780 | Inhibition of 5-HT2A receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID772813 | Displacement of [3H]-citalopram from human SERT expressed in HEK cell membranes | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452495 | Inhibition of CB1 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772789 | Inhibition of dopamine D3 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452497 | Inhibition of D1 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772788 | Inhibition of dopamine D4 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID772795 | Inhibition of adrenergic alpha2A receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716312 | Binding affinity to alpha1B adrenergic receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772768 | Inhibition of mu opioid receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452496 | Inhibition of CB2 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772784 | Inhibition of histamine H3 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID772779 | Inhibition of 5-HT2B receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID772794 | Inhibition of adrenergic alpha2C receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452499 | Inhibition of DAT at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452470 | Selectivity, ratio of Ki for sigma 1 to Ki for sigma 2 | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772781 | Inhibition of 5-HT1B receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716311 | Binding affinity to alpha1A adrenergic | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID716584 | Binding affinity to 5-HT5A receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452467 | Binding affinity to sigma 1 receptor | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716355 | Binding affinity to NET | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772815 | Displacement of [3H]-WIN-35,428 from human DAT expressed in HEK cell membranes | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716333 | Binding affinity to 5-HT2A receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772787 | Inhibition of dopamine D5 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID772774 | Inhibition of muscarinic M2 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452476 | Inhibition of 5HT1E receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772776 | Inhibition of 5-HT7 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID716586 | Binding affinity to delta opioid receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772782 | Inhibition of 5-HT1A receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID772792 | Inhibition of Ca2+ channel (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452484 | Inhibition of 5HT7 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452505 | Inhibition of Kappa opioid receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772785 | Inhibition of histamine H2 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452472 | Inhibition of 5HT1A receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716585 | Binding affinity to 5-HT6 receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID772770 | Inhibition of delta opioid receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452494 | Inhibition of Ca2+ channel at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716583 | Binding affinity to 5-HT2C receptor | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452509 | Inhibition of phencyclidine binding site of NMDA receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID452501 | Inhibition of histamine H1 receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772797 | Inhibition of adrenergic alpha1B receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID772786 | Inhibition of histamine H1 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID772793 | Inhibition of adrenergic alpha2B receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID452478 | Inhibition of 5HT2B receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID716344 | Binding affinity to SERT | 2012 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
| A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs). |
| AID452488 | Inhibition of Alpha2A adrenoceptor receptor at 10 uM | 2010 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 20, Issue:1
| Oxo-bridged isomers of aza-trishomocubane sigma (sigma) receptor ligands: Synthesis, in vitro binding, and molecular modeling. |
| AID772773 | Inhibition of muscarinic M3 receptor (unknown origin) by PDSP assay | 2013 | Bioorganic & medicinal chemistry, Oct-01, Volume: 21, Issue:19
| N-substituted 8-aminopentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecanes as σ receptor ligands with potential neuroprotective effects. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1508628 | Confirmatory qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1508629 | Cell Viability qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1508627 | Counterscreen qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: GLuc-NoTag assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |