1,3,5-Trifluorobenzene is a colorless liquid with a pungent odor. It is a useful building block in organic synthesis and is used in the preparation of various pharmaceuticals and agrochemicals. It can be synthesized through various methods, including the direct fluorination of benzene or the reaction of 1,3,5-tribromobenzene with potassium fluoride. 1,3,5-trifluorobenzene is a potent inhibitor of the enzyme cytochrome P450, which plays a key role in the metabolism of drugs and other chemicals. Due to its biological activity, it is studied as a potential lead compound for the development of new drugs. The compound's unique electronic and structural properties make it an important subject of study in fields like physical chemistry, where it is used as a model system to investigate interactions and reactions. 1,3,5-trifluorobenzene's potential as a building block in various areas of chemistry makes it a significant and intriguing compound.'
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| ID Source | ID |
|---|---|
| PubMed CID | 9745 |
| SCHEMBL ID | 449836 |
| MeSH ID | M0509699 |
| Synonym |
|---|
| EN300-25659 |
| 1,3,5-trifluorobenzene |
| benzene, 1,3,5-trifluoro- |
| nsc10264 |
| 1,5-trifluorobenzene |
| sym-trifluorobenzene |
| benzene,3,5-trifluoro- |
| 372-38-3 |
| nsc-10264 |
| 1,3,5-trifluoro benzene |
| 1,3,5-trifluorobenzene, 97% |
| T1039 |
| AKOS005258293 |
| A823578 |
| bn94c411f8 , |
| einecs 206-751-2 |
| unii-bn94c411f8 |
| nsc 10264 |
| FT-0606510 |
| 1,3,5-tri-fluorobenzene |
| SCHEMBL449836 |
| 1,3,5-trifluorobenzene # |
| W-106556 |
| mfcd00000333 |
| DTXSID90190686 |
| AMY12436 |
| PS-10252 |
| Q27274766 |
| 4-(dihexylamino)benzoicacid |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (32.43) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||