Page last updated: 2024-12-07

1,1,2-triphenylbut-1-ene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

1,1,2-Triphenylbut-1-ene is a **synthetic organic compound** with the molecular formula C22H20. Here's a breakdown of its structure and potential importance in research:

**Structure:**

* **Triphenyl:** This part of the name indicates three phenyl groups (C6H5) attached to the molecule.
* **But-1-ene:** This indicates a four-carbon chain (but-) with a double bond at the first carbon (1-ene).

The structure can be represented as:

```
Ph
|
Ph - C - CH - CH3
|
Ph
```

Where Ph represents a phenyl group.

**Importance in Research:**

1,1,2-Triphenylbut-1-ene is not a widely studied compound, and its specific importance in research is difficult to determine without further context. However, it's worth noting that:

* **Potential for Studying Reactivity:** Due to the presence of multiple phenyl groups and the double bond, this compound could be a good model for studying various chemical reactions, especially those involving electrophilic attack or the formation of carbocations.
* **Possible Precursor:** It could serve as a starting material for synthesizing other organic compounds with complex structures.
* **Stereochemistry:** The presence of chiral centers in this molecule allows for the exploration of stereoisomerism (different spatial arrangements of atoms) and their impact on chemical properties and reactions.

**To understand its specific relevance, you'd need more information about the research context, such as:**

* **What specific properties or reactions are being studied?**
* **What are the goals of the research?**
* **Is it being used as a reagent, catalyst, or product?**

If you can provide more context, I can give you a more accurate and specific explanation of its importance in research.

Cross-References

ID SourceID
PubMed CID124958
CHEMBL ID418153
MeSH IDM0109475

Synonyms (7)

Synonym
1,1,2-tpe
CHEMBL418153
63019-13-6
benzene, 1,1',1''-(1-ethyl-1-ethenyl-2-ylidene)tris-
1,1,2-triphenylbut-1-ene
triphenylbutene
DTXSID70212259
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID123560Anti-neoplastic effect in estrogen and progesterone receptor positive hormone-dependent postmenopausal human mammary carcinoma bearing mice at 2.2 mg/kg/day1982Journal of medicinal chemistry, Sep, Volume: 25, Issue:9
1,1,2-triphenylbut-1-enes: relationship between structure, estradiol receptor affinity, and mammary tumor inhibiting properties.
AID71147Binding affinity against Estrogen receptor in calf-uterine cytosol relative to 17-beta-estradiol using [3H]estradiol.1982Journal of medicinal chemistry, Sep, Volume: 25, Issue:9
1,1,2-triphenylbut-1-enes: relationship between structure, estradiol receptor affinity, and mammary tumor inhibiting properties.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]