Page last updated: 2024-10-24

oxidoreductase complex

Definition

Target type: cellularcomponent

Any protein complex that possesses oxidoreductase activity. [GOC:bhm, PMID:18982432]

Oxidoreductase complexes are multi-protein assemblies that catalyze redox reactions, which involve the transfer of electrons between molecules. These complexes are found in various cellular compartments, including the mitochondria, endoplasmic reticulum, and cytoplasm. The specific cellular component of an oxidoreductase complex can vary depending on the specific complex and its function. For example, some oxidoreductase complexes are embedded in the mitochondrial inner membrane and participate in electron transport chain, while others are localized in the cytoplasm and involved in metabolic pathways. The cellular component of an oxidoreductase complex is determined by the specific proteins that constitute the complex and their interactions with other cellular structures. These interactions are crucial for the proper assembly and function of the complex. The cellular component of an oxidoreductase complex can also be influenced by factors such as the cellular environment and the presence of specific cofactors.'
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Proteins (2)

ProteinDefinitionTaxonomy
L-lactate dehydrogenase B chainAn L-lactate dehydrogenase B chain that is encoded in the genome of human. [PRO:DNx, UniProtKB:P07195]Homo sapiens (human)
L-lactate dehydrogenase A chainAn L-lactate dehydrogenase A chain that is encoded in the genome of human. [PRO:DNx, UniProtKB:P00338]Homo sapiens (human)

Compounds (18)

CompoundDefinitionClassesRoles
malonic aciddicarboxylic acid : Any carboxylic acid containing two carboxy groups.

malonic acid : An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
alpha,omega-dicarboxylic acidhuman metabolite
oxamic acidoxamic acid : A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.

Oxamic Acid: Amino-substituted glyoxylic acid derivative.
dicarboxylic acid monoamideEscherichia coli metabolite
gossypolGossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
guanidine hydrochlorideone-carbon compound;
organic chloride salt
protein denaturant
adenosine monophosphateAdenosine Monophosphate: Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate
adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
1-hydroxy-2-naphthoic acid1-hydroxy-2-naphthoic acid : A naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms.

1-hydroxy-2-naphthoic acid: RN given refers to parent cpd
hydroxy monocarboxylic acid;
naphthoic acid;
naphthols
bacterial xenobiotic metabolite;
fungal xenobiotic metabolite
dronabinolDelta(9)-tetrahydrocannabinol : A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. The principal psychoactive constituent of the cannabis plant, it is used for treatment of anorexia associated with AIDS as well as nausea and vomiting associated with cancer chemotherapy.

Dronabinol: A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound.
benzochromene;
diterpenoid;
phytocannabinoid;
polyketide
cannabinoid receptor agonist;
epitope;
hallucinogen;
metabolite;
non-narcotic analgesic
cannabichromene1-benzopyran
delta(9)-tetrahydrocannabinolic acidDelta(9)-tetrahydrocannabinolic acid : A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant.benzochromene;
diterpenoid;
hydroxy monocarboxylic acid;
phytocannabinoid;
polyketide
anti-inflammatory agent;
biomarker;
metabolite;
neuroprotective agent
gossylic nitrile-1,1'-diacetategossylic nitrile-1,1'-diacetate: inhibits human immunodeficiency virus Type I replication; structure given in first source
cannabidiolcannabidiol : An cannabinoid that is cyclohexene which is substituted by a methyl group at position 1, a 2,6-dihydroxy-4-pentylphenyl group at position 3, and a prop-1-en-2-yl group at position 4.

Cannabidiol: Compound isolated from Cannabis sativa extract.
olefinic compound;
phytocannabinoid;
resorcinols
antimicrobial agent;
plant metabolite
rutinHydroxyethylrutoside: Monohydroxyethyl derivative of rutin. Peripheral circulation stimulant used in treatment of venous disorders.disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone
antioxidant;
metabolite
3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propylnaphthalene-1-carboxylic acid3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propylnaphthalene-1-carboxylic acid: inhibits lactate dehydrogenase A
adenosine monophosphateadenosine 5'-monophosphate(2-) : A nucleoside 5'-monophosphate(2-) that results from the removal of two protons from the phosphate group of adenosine 5'-monophosphate (AMP).nucleoside 5'-monophosphate(2-)cofactor;
fundamental metabolite;
human metabolite
methyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1h-indole-2-carboxylatemethyl 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylate: inhibits lactate dehydrogenase A; structure in first source
galloflavingalloflavin: structure in first source
gossylic iminolactonegossylic iminolactone: inhibits human immunodeficiency virus type I replication; structure given in first source
gossylic lactonegossylic lactone: inhibits human immunodeficiency virus type I replication; structure given in first source