Page last updated: 2024-10-06

mTOR signaling pathway

Proteins (48)

ProteinSynonymsTaxonomy
Insulin receptor substrate 1IRS-1Homo sapiens (human)
Target of rapamycin complex 2 subunit MAPKAP1TORC2 subunit MAPKAP1; Mitogen-activated protein kinase 2-associated protein 1; Stress-activated map kinase-interacting protein 1; SAPK-interacting protein 1; mSIN1Homo sapiens (human)
Serine/threonine-protein kinase Sgk1EC 2.7.11.1; Serum/glucocorticoid-regulated kinase 1Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Homo sapiens (human)
3-phosphoinositide-dependent protein kinase 1hPDK1; EC 2.7.11.1Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Eukaryotic translation initiation factor 4EeIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding proteinHomo sapiens (human)
Protein kinase C alpha typePKC-A; PKC-alpha; EC 2.7.11.13Homo sapiens (human)
Cyclin-dependent kinase 2EC 2.7.11.22; Cell division protein kinase 2; p33 protein kinaseHomo sapiens (human)
Mitogen-activated protein kinase 3 MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1Homo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 1MAP kinase kinase 1; MAPKK 1; MKK1; EC 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1Homo sapiens (human)
Programmed cell death protein 4Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15aHomo sapiens (human)
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6Homo sapiens (human)
Eukaryotic elongation factor 2 kinaseeEF-2 kinase; eEF-2K; EC 2.7.11.20; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinaseHomo sapiens (human)
Serine/threonine-protein kinase ULK1EC 2.7.11.1; Autophagy-related protein 1 homolog; ATG1; hATG1; Unc-51-like kinase 1Homo sapiens (human)
Elongation factor 2EF-2Homo sapiens (human)
Ribosomal protein S6 kinase beta-1S6K-beta-1; S6K1; EC 2.7.11.1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KAHomo sapiens (human)
G1/S-specific cyclin-E1Homo sapiens (human)
Serine/threonine-protein kinase mTOREC 2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1Homo sapiens (human)
Ribosomal protein S6 kinase alpha-1S6K-alpha-1; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; Ribosomal S6 kinase 1; RSK-1Homo sapiens (human)
DEP domain-containing mTOR-interacting proteinDEP domain-containing protein 6Homo sapiens (human)
Eukaryotic translation initiation factor 4BeIF-4BHomo sapiens (human)
Proline-rich AKT1 substrate 140 kDa proline-rich AKT substrateHomo sapiens (human)
14-3-3 protein sigmaEpithelial cell marker protein 1; StratifinHomo sapiens (human)
Cytochrome cHomo sapiens (human)
Sterol regulatory element-binding protein 1SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1Homo sapiens (human)
Eukaryotic initiation factor 4A-IeIF-4A-I; eIF4A-I; EC 3.6.4.13; ATP-dependent RNA helicase eIF4A-1Homo sapiens (human)
Phospholipase D1PLD 1; hPLD1; EC 3.1.4.4; Choline phosphatase 1; Phosphatidylcholine-hydrolyzing phospholipase D1Homo sapiens (human)
Rapamycin-insensitive companion of mTORAVO3 homolog; hAVO3Homo sapiens (human)
Regulatory-associated protein of mTORRaptor; p150 target of rapamycin (TOR)-scaffold proteinHomo sapiens (human)
Target of rapamycin complex subunit LST8TORC subunit LST8; G protein beta subunit-like; Gable; Protein GbetaL; Mammalian lethal with SEC13 protein 8; mLST8Homo sapiens (human)
CAP-Gly domain-containing linker protein 1Cytoplasmic linker protein 1; Cytoplasmic linker protein 170 alpha-2; CLIP-170; Reed-Sternberg intermediate filament-associated protein; RestinHomo sapiens (human)
Eukaryotic translation initiation factor 4E-binding protein 14E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-IHomo sapiens (human)
GTP-binding protein RhebRas homolog enriched in brainHomo sapiens (human)
Protein PMLPromyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19Homo sapiens (human)
RB1-inducible coiled-coil protein 1FAK family kinase-interacting protein of 200 kDa; FIP200Homo sapiens (human)
Transcriptional repressor protein YY1Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and yang 1; YY-1Homo sapiens (human)
Autophagy-related protein 13Homo sapiens (human)
TuberinTuberous sclerosis 2 proteinHomo sapiens (human)
Proline-rich protein 5Protein observed with Rictor-1; Protor-1Homo sapiens (human)
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3Homo sapiens (human)
Ras-related GTP-binding protein ARag A; RagA; EC 3.6.5.-; Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1Homo sapiens (human)
HamartinTuberous sclerosis 1 proteinHomo sapiens (human)
Polymerase delta-interacting protein 346 kDa DNA polymerase delta interaction protein; p46; S6K1 Aly/REF-like target; SKARHomo sapiens (human)
Ras-related GTP-binding protein CRag C; RagC; EC 3.6.5.-; GTPase-interacting protein 2; TIB929Homo sapiens (human)
DNA damage-inducible transcript 4 proteinHIF-1 responsive protein RTP801; Protein regulated in development and DNA damage response 1; REDD-1Homo sapiens (human)
RNA polymerase I-specific transcription initiation factor RRN3Transcription initiation factor IA; TIF-IAHomo sapiens (human)

Compounds (0)

CompoundDescription