Page last updated: 2024-10-06

Sialic acid metabolism

Proteins (13)

ProteinSynonymsTaxonomy
Lysosomal protective proteinEC 3.4.16.5; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A; Protective protein cathepsin A; PPCA; Protective protein for beta-galactosidaseHomo sapiens (human)
Beta-galactosidaseEC 3.2.1.23; Acid beta-galactosidase; Lactase; Elastin receptor 1Homo sapiens (human)
N-acylneuraminate-9-phosphataseEC 3.1.3.29; Haloacid dehalogenase-like hydrolase domain-containing protein 4; Neu5Ac-9-PaseHomo sapiens (human)
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseUDP-GlcNAc-2-epimerase/ManAc kinaseHomo sapiens (human)
Sialidase-4EC 3.2.1.18; N-acetyl-alpha-neuraminidase 4Homo sapiens (human)
Sialidase-3EC 3.2.1.18; Ganglioside sialidasedis; Membrane sialidase; N-acetyl-alpha-neuraminidase 3Homo sapiens (human)
Sialidase-2EC 3.2.1.18; Cytosolic sialidase; N-acetyl-alpha-neuraminidase 2Homo sapiens (human)
SialinH(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Membrane glycoprotein HP59; Solute carrier family 17 member 5; Vesicular H(+)/Aspartate-glutamate cotransporterHomo sapiens (human)
Sialidase-1EC 3.2.1.18; Acetylneuraminyl hydrolase; G9 sialidase; Lysosomal sialidase; N-acetyl-alpha-neuraminidase 1Homo sapiens (human)
N-acylneuraminate cytidylyltransferaseEC 2.7.7.43; CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthaseHomo sapiens (human)
N-acetylneuraminate lyaseNALase; EC 4.1.3.3; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialate-pyruvate lyase; Sialic acid aldolase; Sialic acid lyaseHomo sapiens (human)
CMP-sialic acid transporterCMP-SA-Tr; CMP-Sia-Tr; Solute carrier family 35 member A1Homo sapiens (human)
Sialic acid synthaseN-acetylneuraminate synthase; 2.5.1.56; N-acetylneuraminate-9-phosphate synthase; 2.5.1.57; N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthaseHomo sapiens (human)

Compounds (12)

CompoundDescription
hydronium ion
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
N-acetylmannosamine 6-phosphate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Cytidine TriphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
N-acetylmannosamineRN given refers to cpd without isomeric designation