Page last updated: 2024-10-06

PPARA activates gene expression

Proteins (98)

ProteinSynonymsTaxonomy
Cytochrome P450 4A11EC 1.14.14.1; 20-hydroxyeicosatetraenoic acid synthase; 20-HETE synthase; CYP4AII; CYPIVA11; Cytochrome P-450HK-omega; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase; 1.14.14Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 25Activator interaction domain-containing protein 1; Activator-recruited cofactor 92 kDa component; ARC92; Mediator complex subunit 25; p78Homo sapiens (human)
Histone deacetylase 3HD3; EC 3.5.1.98; RPD3-2; SMAP45Homo sapiens (human)
Nuclear receptor ROR-alphaNuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; Retinoid-related orphan receptor-alphaHomo sapiens (human)
Bile acid receptorFarnesoid X-activated receptor; Farnesol receptor HRR-1; Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor-interacting protein 14; RXR-interacting protein 14Homo sapiens (human)
F-box-like/WD repeat-containing protein TBL1XR1Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1Homo sapiens (human)
Phosphatidylcholine translocator ABCB4EC 7.6.2.1; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3Homo sapiens (human)
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6Homo sapiens (human)
Cytochrome P450 1A1CYPIA1; EC 1.14.14.1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1; Hydroperoxy icosatetraenoate dehydratase; 4.2.1.152Homo sapiens (human)
Retinoic acid receptor RXR-alphaNuclear receptor subfamily 2 group B member 1; Retinoid X receptor alphaHomo sapiens (human)
Peroxisome proliferator-activated receptor alphaPPAR-alpha; Nuclear receptor subfamily 1 group C member 1Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Cyclin-dependent kinase 19EC 2.7.11.22; CDC2-related protein kinase 6; Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; Cyclin-dependent kinase 11; Death-preventing kinaseHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 23Activator-recruited cofactor 130 kDa component; ARC130; Cofactor required for Sp1 transcriptional activation subunit 3; CRSP complex subunit 3; Mediator complex subunit 23; Protein sur-2 homolog; hSur-2; Transcriptional coactivator CRSP130; Vitamin D3 recHomo sapiens (human)
Medium-chain specific acyl-CoA dehydrogenase, mitochondrialMCAD; EC 1.3.8.7; Medium chain acyl-CoA dehydrogenase; MCADHHomo sapiens (human)
Cytochrome P450 7A124-hydroxycholesterol 7-alpha-hydroxylase; 1.14.14.26; CYPVII; Cholesterol 7-alpha-hydroxylase; Cholesterol 7-alpha-monooxygenase; 1.14.14.23Homo sapiens (human)
Long-chain-fatty-acid--CoA ligase 1EC 6.2.1.3; Acyl-CoA synthetase 1; ACS1; Arachidonate--CoA ligase; 6.2.1.15; Long-chain acyl-CoA synthetase 1; LACS 1; Long-chain acyl-CoA synthetase 2; LACS 2; Long-chain fatty acid-CoA ligase 2; Palmitoyl-CoA ligase 1; Palmitoyl-CoA ligase 2; Phytanate-Homo sapiens (human)
AngiotensinogenSerpin A8Homo sapiens (human)
Acyl-CoA (8-3)-desaturaseEC 1.14.19.44; Delta(5) fatty acid desaturase; D5D; Delta(5) desaturase; Delta-5 desaturase; Fatty acid desaturase 1Homo sapiens (human)
Fatty acid-binding protein, liverFatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABPHomo sapiens (human)
Platelet glycoprotein 4Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptorHomo sapiens (human)
Aryl hydrocarbon receptorAh receptor; AhR; Class E basic helix-loop-helix protein 76; bHLHe76Homo sapiens (human)
Squalene synthaseSQS; SS; EC 2.5.1.21; FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; Farnesyl-diphosphate farnesyltransferase 1Homo sapiens (human)
Apolipoprotein A-IApo-AI; ApoA-I; Apolipoprotein A1Homo sapiens (human)
Cyclin-CSRB11 homolog; hSRB11Homo sapiens (human)
Nuclear receptor coactivator 1NCoA-1; EC 2.3.1.48; Class E basic helix-loop-helix protein 74; bHLHe74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid receptor coactivator 1; SRC-1Homo sapiens (human)
Long-chain fatty acid transport protein 1FATP-1; Fatty acid transport protein 1; EC 6.2.1.15; Solute carrier family 27 member 1Homo sapiens (human)
Nuclear receptor coactivator 2NCoA-2; Class E basic helix-loop-helix protein 75; bHLHe75; Transcriptional intermediary factor 2; hTIF2Homo sapiens (human)
UDP-glucuronosyltransferase 1A9UGT1A9; EC 2.4.1.17; UDP-glucuronosyltransferase 1-9; UDPGT 1-9; UGT1*9; UGT1-09; UGT1.9; UDP-glucuronosyltransferase 1-I; UGT-1I; UGT1I; lugP4Homo sapiens (human)
Nuclear receptor corepressor 1N-CoR; N-CoR1Homo sapiens (human)
Steroid hormone receptor ERR1Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1Homo sapiens (human)
Carnitine O-palmitoyltransferase 2, mitochondrialEC 2.3.1.21; Carnitine palmitoyltransferase II; CPT IIHomo sapiens (human)
Cyclin-dependent kinase 8EC 2.7.11.22; EC 2.7.11.23; Cell division protein kinase 8; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; Protein kinase K35Homo sapiens (human)
Carnitine O-palmitoyltransferase 1, liver isoformCPT1-L; EC 2.3.1.21; Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1AHomo sapiens (human)
Thioredoxin reductase 1, cytoplasmicTR; EC 1.8.1.9; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1Homo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Transcription factor Sp1Homo sapiens (human)
NADP-dependent malic enzymeNADP-ME; EC 1.1.1.40; Malic enzyme 1Homo sapiens (human)
Hydroxymethylglutaryl-CoA synthase, mitochondrialHMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthaseHomo sapiens (human)
Hydroxymethylglutaryl-CoA synthase, cytoplasmicHMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthaseHomo sapiens (human)
Thyroid hormone receptor-associated protein 3BCLAF1 and THRAP3 family member 2; Thyroid hormone receptor-associated protein complex 150 kDa component; Trap150Homo sapiens (human)
Sulfotransferase 2A1ST2A1; EC 2.8.2.2; Bile salt sulfotransferase; 2.8.2.14; Dehydroepiandrosterone sulfotransferase; DHEA-ST; DHEA-ST8; Hydroxysteroid Sulfotransferase; HST; ST2; SULT2A3Homo sapiens (human)
Nuclear receptor coactivator 3NCoA-3; EC 2.3.1.48; ACTR; Amplified in breast cancer 1 protein; AIB-1; CBP-interacting protein; pCIP; Class E basic helix-loop-helix protein 42; bHLHe42; Receptor-associated coactivator 3; RAC-3; Steroid receptor coactivator protein 3; SRC-3; Thyroid horHomo sapiens (human)
Peroxisome proliferator-activated receptor gamma coactivator 1-betaPGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PGC-1-related estrogen receptor alpha coactivatorHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 1Activator-recruited cofactor 205 kDa component; ARC205; Mediator complex subunit 1; Peroxisome proliferator-activated receptor-binding protein; PBP; PPAR-binding protein; Thyroid hormone receptor-associated protein complex 220 kDa component; Trap220; ThyrHomo sapiens (human)
Nuclear respiratory factor 1NRF-1; Alpha palindromic-binding protein; Alpha-palHomo sapiens (human)
Apolipoprotein A-IIApo-AII; ApoA-II; Apolipoprotein A2Homo sapiens (human)
5-aminolevulinate synthase, nonspecific, mitochondrialALAS-H; EC 2.3.1.37; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 22Mediator complex subunit 22; Surfeit locus protein 5; Surf-5Homo sapiens (human)
Ral guanine nucleotide dissociation stimulator-like 1RalGDS-like 1Homo sapiens (human)
Perilipin-2Adipophilin; Adipose differentiation-related protein; ADRPHomo sapiens (human)
Aryl hydrocarbon receptor repressorAhR repressor; AhRR; Class E basic helix-loop-helix protein 77; bHLHe77Homo sapiens (human)
Apolipoprotein A-VApo-AV; ApoA-V; Apolipoprotein A5; Regeneration-associated protein 3Homo sapiens (human)
Angiopoietin-related protein 4Angiopoietin-like protein 4; Hepatic fibrinogen/angiopoietin-related protein; HFARPHomo sapiens (human)
Ankyrin repeat domain-containing protein 1Cardiac ankyrin repeat protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear proteinHomo sapiens (human)
Constitutive coactivator of peroxisome proliferator-activated receptor gammaConstitutive coactivator of PPAR-gamma; Constitutive coactivator of PPARG; PPARG constitutive coactivator 1; PGCC1; Protein FAM120BHomo sapiens (human)
Aryl hydrocarbon receptor nuclear translocator-like protein 1Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1; Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-containing protein 3; bHLH-PAS protein JAP3Homo sapiens (human)
Neuronal PAS domain-containing protein 2Neuronal PAS2; Basic-helix-loop-helix-PAS protein MOP4; Class E basic helix-loop-helix protein 9; bHLHe9; Member of PAS protein 4; PAS domain-containing protein 4Homo sapiens (human)
Phospholipid-transporting ATPase ABCA1EC 7.6.2.1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; Cholesterol efflux regulatory proteinHomo sapiens (human)
G0/G1 switch protein 2G0/G1 switch regulatory protein 2; Putative lymphocyte G0/G1 switch geneHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 19Lung cancer metastasis-related protein 1; Mediator complex subunit 19Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 7hMED7; Activator-recruited cofactor 34 kDa component; ARC34; Cofactor required for Sp1 transcriptional activation subunit 9; CRSP complex subunit 9; Mediator complex subunit 7; RNA polymerase transcriptional regulation mediator subunit 7 homolog; TranscriHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 14Activator-recruited cofactor 150 kDa component; ARC150; Cofactor required for Sp1 transcriptional activation subunit 2; CRSP complex subunit 2; Mediator complex subunit 14; RGR1 homolog; hRGR1; Thyroid hormone receptor-associated protein complex 170 kDa cHomo sapiens (human)
F-box-like/WD repeat-containing protein TBL1XSMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linkedHomo sapiens (human)
Peroxisomal membrane protein 11AHsPEX11p; 28 kDa peroxisomal integral membrane protein; PMP28; Peroxin-11A; Peroxisomal biogenesis factor 11A; Protein PEX11 homolog alpha; PEX11-alphaHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 24Activator-recruited cofactor 100 kDa component; ARC100; Cofactor required for Sp1 transcriptional activation subunit 4; CRSP complex subunit 4; Mediator complex subunit 24; Thyroid hormone receptor-associated protein 4; Thyroid hormone receptor-associatedHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 21Death receptor 6Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 6Activator-recruited cofactor 33 kDa component; ARC33; Mediator complex subunit 6; hMed6; Renal carcinoma antigen NY-REN-28Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 26Activator-recruited cofactor 70 kDa component; ARC70; Cofactor required for Sp1 transcriptional activation subunit 7; CRSP complex subunit 7; Mediator complex subunit 26; Transcriptional coactivator CRSP70Homo sapiens (human)
Nuclear transcription factor Y subunit alphaCAAT box DNA-binding protein subunit A; Nuclear transcription factor Y subunit A; NF-YAHomo sapiens (human)
Nuclear transcription factor Y subunit betaCAAT box DNA-binding protein subunit B; Nuclear transcription factor Y subunit B; NF-YBHomo sapiens (human)
Glioma pathogenesis-related protein 1GliPR 1; Protein RTVP-1Homo sapiens (human)
G protein pathway suppressor 2GPS-2Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 21Mediator complex subunit 21; RNA polymerase II holoenzyme component SRB7; RNAPII complex component SRB7; hSrb7Homo sapiens (human)
Nuclear transcription factor Y subunit gammaCAAT box DNA-binding protein subunit C; Nuclear transcription factor Y subunit C; NF-YC; Transactivator HSM-1/2Homo sapiens (human)
Four and a half LIM domains protein 2FHL-2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; SLIM-3Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 27Cofactor required for Sp1 transcriptional activation subunit 8; CRSP complex subunit 8; Mediator complex subunit 27; P37 TRAP/SMCC/PC2 subunit; Transcriptional coactivator CRSP34Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 13-likeMediator complex subunit 13-like; Thyroid hormone receptor-associated protein 2; Thyroid hormone receptor-associated protein complex 240 kDa component-likeHomo sapiens (human)
T-lymphoma invasion and metastasis-inducing protein 2TIAM-2; SIF and TIAM1-like exchange factorHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 12Activator-recruited cofactor 240 kDa component; ARC240; CAG repeat protein 45; Mediator complex subunit 12; OPA-containing protein; Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230; Trinucleotide repeat-containing gene 11 proHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 8Activator-recruited cofactor 32 kDa component; ARC32; Mediator complex subunit 8Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 30Mediator complex subunit 30; TRAP/Mediator complex component TRAP25; Thyroid hormone receptor-associated protein 6; Thyroid hormone receptor-associated protein complex 25 kDa component; Trap25Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 15Activator-recruited cofactor 105 kDa component; ARC105; CTG repeat protein 7a; Mediator complex subunit 15; Positive cofactor 2 glutamine/Q-rich-associated protein; PC2 glutamine/Q-rich-associated protein; TPA-inducible gene 1 protein; TIG-1; TrinucleotidHomo sapiens (human)
Tribbles homolog 3TRB-3; Neuronal cell death-inducible putative kinase; SINK; p65-interacting inhibitor of NF-kappa-BHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 10Mediator complex subunit 10; Transformation-related gene 17 protein; TRG-17; Transformation-related gene 20 protein; TRG-20Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 18Mediator complex subunit 18; p28bHomo sapiens (human)
Helicase with zinc finger domain 2ATP-dependent helicase PRIC285; Helicase with zinc finger 2, transcriptional coactivator; PPAR-alpha-interacting complex protein 285; PPAR-gamma DNA-binding domain-interacting protein 1; PDIP1; PPAR-gamma DBD-interacting protein 1; Peroxisomal proliferatoHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 28Endothelial-derived protein 1; Mediator complex subunit 28; Merlin and Grb2-interacting cytoskeletal protein; Magicin; Tumor angiogenesis marker EG-1Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 20Mediator complex subunit 20; TRF-proximal protein homolog; hTRFPHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 4Activator-recruited cofactor 36 kDa component; ARC36; Mediator complex subunit 4; TRAP/SMCC/PC2 subunit p36 subunit; Vitamin D3 receptor-interacting protein complex 36 kDa component; DRIP36Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 17Activator-recruited cofactor 77 kDa component; ARC77; Cofactor required for Sp1 transcriptional activation subunit 6; CRSP complex subunit 6; Mediator complex subunit 17; Thyroid hormone receptor-associated protein complex 80 kDa component; Trap80; TranscHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 9Mediator complex subunit 9Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 29Intersex-like protein; Mediator complex subunit 29Homo sapiens (human)
Grainyhead-like protein 1 homologMammalian grainyhead; NH32; Transcription factor CP2-like 2; Transcription factor LBP-32Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 11Mediator complex subunit 11Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 13Activator-recruited cofactor 250 kDa component; ARC250; Mediator complex subunit 13; Thyroid hormone receptor-associated protein 1; Thyroid hormone receptor-associated protein complex 240 kDa component; Trap240; Vitamin D3 receptor-interacting protein comHomo sapiens (human)
Mediator of RNA polymerase II transcription subunit 16Mediator complex subunit 16; Thyroid hormone receptor-associated protein 5; Thyroid hormone receptor-associated protein complex 95 kDa component; Trap95; Vitamin D3 receptor-interacting protein complex 92 kDa component; DRIP92Homo sapiens (human)
Mediator of RNA polymerase II transcription subunit 31Mediator complex subunit 31; Mediator complex subunit SOH1; hSOH1Homo sapiens (human)

Compounds (0)

CompoundDescription