Pathways > Defective Intrinsic Pathway for Apoptosis
Page last updated: 2024-10-06

Defective Intrinsic Pathway for Apoptosis

Proteins (20)

ProteinSynonymsTaxonomy
Peroxiredoxin-2EC 1.11.1.24; Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1; Thioredoxin-dependent peroxiredoxin 2Homo sapiens (human)
Amyloid-beta precursor proteinAPP; ABPP; APPI; Alzheimer disease amyloid protein; Amyloid precursor protein; Amyloid-beta A4 protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-IIHomo sapiens (human)
Cyclin-dependent-like kinase 5 EC 2.7.11.1; Cell division protein kinase 5; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunitHomo sapiens (human)
Tumor necrosis factor ligand superfamily member 6Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasLHomo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Calpain-1 catalytic subunitEC 3.4.22.52; Calcium-activated neutral proteinase 1; CANP 1; Calpain mu-type; Calpain-1 large subunit; Cell proliferation-inducing gene 30 protein; Micromolar-calpain; muCANPHomo sapiens (human)
M-phase inducer phosphatase 2EC 3.1.3.48; Dual specificity phosphatase Cdc25BHomo sapiens (human)
M-phase inducer phosphatase 3EC 3.1.3.48; Dual specificity phosphatase Cdc25CHomo sapiens (human)
Cyclin-dependent kinase 5 activator 1CDK5 activator 1; Cyclin-dependent kinase 5 regulatory subunit 1; TPKII regulatory subunitHomo sapiens (human)
Forkhead box protein O3AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1Homo sapiens (human)
Peroxiredoxin-1EC 1.11.1.24; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; Thioredoxin-dependent peroxiredoxin 1Homo sapiens (human)
Bcl-2-like protein 11Bcl2-L-11; Bcl2-interacting mediator of cell deathHomo sapiens (human)
Calpain-2 catalytic subunitEC 3.4.22.53; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; Calpain large polypeptide L2; Calpain-2 large subunit; Millimolar-calpain; M-calpainHomo sapiens (human)
M-phase inducer phosphatase 1EC 3.1.3.48; Dual specificity phosphatase Cdc25AHomo sapiens (human)
CalpastatinCalpain inhibitor; Sperm BS-17 componentHomo sapiens (human)
14-3-3 protein epsilon14-3-3EHomo sapiens (human)
Superoxide dismutase [Mn], mitochondrialEC 1.15.1.1Homo sapiens (human)
Complement component 1 Q subcomponent-binding protein, mitochondrialASF/SF2-associated protein p32; Glycoprotein gC1qBP; C1qBP; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; gC1q-R protein; p33; SF2AP32Homo sapiens (human)
Golgin subfamily A member 2130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; Golgin-95Homo sapiens (human)
Lamin-B1Homo sapiens (human)

Compounds (4)

CompoundDescription
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
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