Page last updated: 2024-10-06

Chromosome Maintenance

Proteins (92)

ProteinSynonymsTaxonomy
Cyclin-dependent kinase 2EC 2.7.11.22; Cell division protein kinase 2; p33 protein kinaseHomo sapiens (human)
Werner syndrome ATP-dependent helicaseEC 3.6.4.12; DNA helicase, RecQ-like type 3; RecQ3; Exonuclease WRN; 3.1.-.-; RecQ protein-like 2Homo sapiens (human)
DNA polymerase delta subunit 4DNA polymerase delta subunit p12Homo sapiens (human)
Protection of telomeres protein 1hPot1; POT1-like telomere end-binding proteinHomo sapiens (human)
Telomerase reverse transcriptaseEC 2.7.7.49; HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2; TP2Homo sapiens (human)
DNA polymerase alpha catalytic subunitEC 2.7.7.7; DNA polymerase alpha catalytic subunit p180Homo sapiens (human)
Replication protein A 70 kDa DNA-binding subunitRP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding proteinHomo sapiens (human)
Telomeric repeat-binding factor 2TTAGGG repeat-binding factor 2; Telomeric DNA-binding proteinHomo sapiens (human)
Serine/threonine-protein phosphatase 6 catalytic subunitPP6C; EC 3.1.3.16Homo sapiens (human)
Replication factor C subunit 5Activator 1 36 kDa subunit; A1 36 kDa subunit; Activator 1 subunit 5; Replication factor C 36 kDa subunit; RF-C 36 kDa subunit; RFC36Homo sapiens (human)
RuvB-like 2EC 3.6.4.12; 48 kDa TATA box-binding protein-interacting protein; 48 kDa TBP-interacting protein; 51 kDa erythrocyte cytosolic protein; ECP-51; INO80 complex subunit J; Repressing pontin 52; Reptin 52; TIP49b; TIP60-associated protein 54-beta; TAP54-betaHomo sapiens (human)
DNA replication ATP-dependent helicase/nuclease DNA2hDNA2; DNA replication ATP-dependent helicase-like homologHomo sapiens (human)
NucleophosminNPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; NumatrinHomo sapiens (human)
Proliferating cell nuclear antigenPCNA; CyclinHomo sapiens (human)
DNA ligase 1EC 6.5.1.1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1Homo sapiens (human)
DNA polymerase delta catalytic subunitEC 2.7.7.7; 3'-5' exodeoxyribonuclease; 3.1.11.-; DNA polymerase subunit delta p125Homo sapiens (human)
Histone H4Homo sapiens (human)
Histone-binding protein RBBP4Chromatin assembly factor 1 subunit C; CAF-1 subunit C; Chromatin assembly factor I p48 subunit; CAF-I 48 kDa subunit; CAF-I p48; Nucleosome-remodeling factor subunit RBAP48; Retinoblastoma-binding protein 4; RBBP-4; Retinoblastoma-binding protein p48Homo sapiens (human)
Histone-binding protein RBBP7Histone acetyltransferase type B subunit 2; Nucleosome-remodeling factor subunit RBAP46; Retinoblastoma-binding protein 7; RBBP-7; Retinoblastoma-binding protein p46Homo sapiens (human)
RuvB-like 1EC 3.6.4.12; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alHomo sapiens (human)
Flap endonuclease 1FEN-1; EC 3.1.-.-; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1Homo sapiens (human)
Transcriptional regulator ATRXEC 3.6.4.12; ATP-dependent helicase ATRX; X-linked helicase II; X-linked nuclear protein; XNP; Znf-HXHomo sapiens (human)
CST complex subunit STN1Oligonucleotide/oligosaccharide-binding fold-containing protein 1; Suppressor of cdc thirteen homologHomo sapiens (human)
Regulator of telomere elongation helicase 1EC 3.6.4.12; Novel helicase-likeHomo sapiens (human)
Telomeric repeat-binding factor 2-interacting protein 1TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; Dopamine receptor-interacting protein 5; Repressor/activator protein 1 homolog; RAP1 homolog; hRap1Homo sapiens (human)
Centromere protein CCENP-C; Centromere autoantigen C; Centromere protein C 1; CENP-C 1; Interphase centromere complex protein 7Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB1RNA polymerase II subunit B1; EC 2.7.7.6; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1; 2.7.7.48Homo sapiens (human)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit APP6-ARS-A; Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A; Ankyrin repeat domain-containing protein 28; Phosphatase interactor targeting protein hnRNP K; PITKHomo sapiens (human)
Serine/threonine-protein phosphatase 6 regulatory subunit 3SAPS domain family member 3; Sporulation-induced transcript 4-associated protein SAPLHomo sapiens (human)
Death domain-associated protein 6Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated proteinHomo sapiens (human)
Histone H3-like centromeric protein ACentromere autoantigen A; Centromere protein A; CENP-AHomo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC4RNA polymerases I, II, and III subunit ABC4; ABC10-alpha; DNA-directed RNA polymerase II subunit K; RNA polymerase II 7.0 kDa subunit; RPB7.0; RPB10alphaHomo sapiens (human)
Centromere protein XCENP-X; FANCM-associated histone fold protein 2; FANCM-interacting histone fold protein 2; Fanconi anemia-associated polypeptide of 10 kDa; Retinoic acid-inducible gene D9 protein homolog; Stimulated by retinoic acid gene 13 protein homologHomo sapiens (human)
DNA-directed RNA polymerase II subunit RPB4RNA polymerase II subunit B4; DNA-directed RNA polymerase II subunit D; RNA polymerase II 16 kDa subunit; RPB16Homo sapiens (human)
Protein Mis18-betaCancer/testis antigen 86; CT86; Opa-interacting protein 5; OIP-5Homo sapiens (human)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; EC 3.6.4.-; Sucrose nonfermenting protein 2 homolog; hSNF2HHomo sapiens (human)
H/ACA ribonucleoprotein complex subunit DKC1EC 5.4.99.-; CBF5 homolog; Dyskerin; Nopp140-associated protein of 57 kDa; Nucleolar protein NAP57; Nucleolar protein family A member 4; snoRNP protein DKC1Homo sapiens (human)
Chromosome transmission fidelity protein 8 homologhCTF8Homo sapiens (human)
Replication protein A 32 kDa subunitRP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB3RNA polymerase II subunit 3; RNA polymerase II subunit B3; DNA-directed RNA polymerase II 33 kDa polypeptide; RPB33; DNA-directed RNA polymerase II subunit C; RPB31Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC1RNA polymerases I, II, and III subunit ABC1; DNA-directed RNA polymerase II 23 kDa polypeptide; DNA-directed RNA polymerase II subunit E; RPB5 homolog; XAP4Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB2EC 2.7.7.6; DNA-directed RNA polymerase II 140 kDa polypeptide; DNA-directed RNA polymerase II subunit B; RNA polymerase II subunit 2; RNA polymerase II subunit B2Homo sapiens (human)
Replication protein A 14 kDa subunitRP-A p14; Replication factor A protein 3; RF-A protein 3Homo sapiens (human)
Replication factor C subunit 4Activator 1 37 kDa subunit; A1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37 kDa subunit; RF-C 37 kDa subunit; RFC37Homo sapiens (human)
Replication factor C subunit 2Activator 1 40 kDa subunit; A1 40 kDa subunit; Activator 1 subunit 2; Replication factor C 40 kDa subunit; RF-C 40 kDa subunit; RFC40Homo sapiens (human)
Replication factor C subunit 1Activator 1 140 kDa subunit; A1 140 kDa subunit; Activator 1 large subunit; Activator 1 subunit 1; DNA-binding protein PO-GA; Replication factor C 140 kDa subunit; RF-C 140 kDa subunit; RFC140; Replication factor C large subunitHomo sapiens (human)
DNA-directed RNA polymerase II subunit RPB9RNA polymerase II subunit B9; DNA-directed RNA polymerase II subunit I; RNA polymerase II 14.5 kDa subunit; RPB14.5Homo sapiens (human)
Replication factor C subunit 3Activator 1 38 kDa subunit; A1 38 kDa subunit; Activator 1 subunit 3; Replication factor C 38 kDa subunit; RF-C 38 kDa subunit; RFC38Homo sapiens (human)
DNA polymerase delta subunit 2DNA polymerase delta subunit p50Homo sapiens (human)
DNA primase small subunitEC 2.7.7.-; DNA primase 49 kDa subunit; p49Homo sapiens (human)
DNA primase large subunitDNA primase 58 kDa subunit; p58Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC3RNA polymerases I, II, and III subunit ABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide; RPB17; RPB8 homolog; hRPB8Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB11-aRNA polymerase II subunit B11-a; RPB11a; DNA-directed RNA polymerase II subunit J-1; RNA polymerase II 13.3 kDa subunitHomo sapiens (human)
Telomeric repeat-binding factor 1NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; Telomeric protein Pin2/TRF1Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC2RNA polymerases I, II, and III subunit ABC2; DNA-directed RNA polymerase II subunit F; DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; RPABC14.4; RPB14.4; RPB6 homolog; RPC15Homo sapiens (human)
DNA-directed RNA polymerase II subunit RPB7RNA polymerase II subunit B7; DNA-directed RNA polymerase II subunit G; RNA polymerase II 19 kDa subunit; RPB19Homo sapiens (human)
DNA-directed RNA polymerases I, II, and III subunit RPABC5RNA polymerases I, II, and III subunit ABC5; DNA-directed RNA polymerase III subunit L; RNA polymerase II 7.6 kDa subunit; RPB7.6; RPB10 homologHomo sapiens (human)
Histone H3.3Homo sapiens (human)
Centromere protein RCENP-R; Beta-3-endonexin; Integrin beta-3-binding protein; Nuclear receptor-interacting factor 3Homo sapiens (human)
DNA polymerase alpha subunit BDNA polymerase alpha 70 kDa subunitHomo sapiens (human)
DNA polymerase delta subunit 3DNA polymerase delta subunit C; DNA polymerase delta subunit p66; DNA polymerase delta subunit p68Homo sapiens (human)
Histone H3.1tH3/t; H3t; H3/g; Histone H3.4Homo sapiens (human)
CST complex subunit CTC1Conserved telomere maintenance component 1; HBV DNAPTP1-transactivated protein BHomo sapiens (human)
Centromere protein WCENP-W; Cancer-up-regulated gene 2 proteinHomo sapiens (human)
Centromere protein PCENP-PHomo sapiens (human)
Mis18-binding protein 1Kinetochore-associated protein KNL-2 homolog; HsKNL-2; P243Homo sapiens (human)
Protein SHQ1 homologHomo sapiens (human)
Centromere protein UCENP-U; Centromere protein of 50 kDa; CENP-50; Interphase centromere complex protein 24; KSHV latent nuclear antigen-interacting protein 1; MLF1-interacting protein; Polo-box-interacting protein 1Homo sapiens (human)
Centromere protein QCENP-QHomo sapiens (human)
CST complex subunit TEN1Protein telomeric pathways with STN1 homolog; Telomere length regulation protein TEN1 homologHomo sapiens (human)
Centromere protein LCENP-L; Interphase centromere complex protein 33Homo sapiens (human)
Centromere protein SCENP-S; Apoptosis-inducing TAF9-like domain-containing protein 1; FANCM-associated histone fold protein 1; FANCM-interacting histone fold protein 1; Fanconi anemia-associated polypeptide of 16 kDaHomo sapiens (human)
Holliday junction recognition protein14-3-3-associated AKT substrate; Fetal liver-expressing gene 1 protein; Up-regulated in lung cancer 9Homo sapiens (human)
Kinetochore scaffold 1ALL1-fused gene from chromosome 15q14 protein; AF15q14; Bub-linking kinetochore protein; Blinkin; Cancer susceptibility candidate gene 5 protein; Cancer/testis antigen 29; CT29; Kinetochore-null protein 1; Protein CASC5; Protein D40/AF15q14Homo sapiens (human)
Chromosome transmission fidelity protein 18 homologhCTF18; CHL12Homo sapiens (human)
Centromere protein ICENP-I; FSH primary response protein 1; Follicle-stimulating hormone primary response protein; Interphase centromere complex protein 19; Leucine-rich primary response protein 1Homo sapiens (human)
Adrenocortical dysplasia protein homologPOT1 and TIN2-interacting proteinHomo sapiens (human)
Centromere protein TCENP-T; Interphase centromere complex protein 22Homo sapiens (human)
Centromere protein NCENP-N; Interphase centromere complex protein 32Homo sapiens (human)
Remodeling and spacing factor 1Rsf-1; HBV pX-associated protein 8; Hepatitis B virus X-associated protein; p325 subunit of RSF chromatin-remodeling complexHomo sapiens (human)
Centromere protein KCENP-K; Interphase centromere complex protein 37; Protein AF-5alpha; p33Homo sapiens (human)
TERF1-interacting nuclear factor 2TRF1-interacting nuclear protein 2Homo sapiens (human)
Centromere protein OCENP-O; Interphase centromere complex protein 36Homo sapiens (human)
Telomerase Cajal body protein 1WD repeat-containing protein 79; WD40 repeat-containing protein antisense to TP53 gene; WRAP53betaHomo sapiens (human)
Sister chromatid cohesion protein DCC1Defective in sister chromatid cohesion protein 1 homologHomo sapiens (human)
Centromere protein HCENP-H; Interphase centromere complex protein 35Homo sapiens (human)
ATP-dependent DNA helicase PIF1 EC 3.6.4.12; DNA repair and recombination helicase PIF1; PIF1/RRM3 DNA helicase-like proteinHomo sapiens (human)
H/ACA ribonucleoprotein complex subunit 3Nucleolar protein 10; Nucleolar protein family A member 3; snoRNP protein NOP10Homo sapiens (human)
Centromere protein MCENP-M; Interphase centromere complex protein 39; Proliferation-associated nuclear element protein 1Homo sapiens (human)
H/ACA ribonucleoprotein complex subunit 2Nucleolar protein family A member 2; snoRNP protein NHP2Homo sapiens (human)
H/ACA ribonucleoprotein complex subunit 1Nucleolar protein family A member 1; snoRNP protein GAR1Homo sapiens (human)
Protein Mis18-alphaFAPP1-associated protein 1Homo sapiens (human)

Compounds (13)

CompoundDescription
hydronium ion
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
deoxyguanosine triphosphate
Guanosine MonophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
thymidine 5'-triphosphateRN given refers to parent cpd
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Uridine Monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
2'-deoxycytidine 5'-triphosphateRN given refers to unlabeled parent cpd
deoxyadenosine diphosphateRN given refers to parent cpd.