Page last updated: 2024-09-03

org 9935 and rolipram

org 9935 has been researched along with rolipram in 5 studies

Compound Research Comparison

Studies
(org 9935)
Trials
(org 9935)
Recent Studies (post-2010)
(org 9935)
Studies
(rolipram)
Trials
(rolipram)
Recent Studies (post-2010) (rolipram)
15011,60417401

Protein Interaction Comparison

ProteinTaxonomyorg 9935 (IC50)rolipram (IC50)
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.2233
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)1.2233
Retina-specific copper amine oxidaseHomo sapiens (human)0.0003
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.0975
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)3.63
ReninHomo sapiens (human)3.5
Tumor necrosis factorHomo sapiens (human)0.35
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Rattus norvegicus (Norway rat)0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4CRattus norvegicus (Norway rat)0.7287
cAMP-specific 3',5'-cyclic phosphodiesterase 4BRattus norvegicus (Norway rat)0.8447
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)1.1942
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.095
Delta-type opioid receptorMus musculus (house mouse)1.5
Delta-type opioid receptorRattus norvegicus (Norway rat)1.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4ARattus norvegicus (Norway rat)0.7287
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)1.1005
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)1.61
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)1.0794
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.835
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AHomo sapiens (human)0.835
cAMP-specific 3',5'-cyclic phosphodiesterase 7BHomo sapiens (human)0.835
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10AHomo sapiens (human)0.835

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furman, BL; Pyne, NJ; Shafiee-Nick, R1
Blease, K; Burke-Gaffney, A; Hellewell, PG1
Conti, M; Hanssen, RG; Hirsch, B; Hsueh, AJ; Kloosterboer, HJ; Tsafriri, A; Van de Kant, M; Wiersma, A1
Adcock, IM; Barnes, PJ; Robichaud, A; Seybold, J; Wright, LC1
Conti, M; DePaolo, LV; Jensen, JT; Schwinof, KM; Stouffer, RL; Zelinski-Wooten, MB1

Other Studies

5 other study(ies) available for org 9935 and rolipram

ArticleYear
Effects of type-selective phosphodiesterase inhibitors on glucose-induced insulin secretion and islet phosphodiesterase activity.
    British journal of pharmacology, 1995, Volume: 115, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Analysis of Variance; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Guanidines; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrazines; Pyridazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Thiophenes

1995
Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterases 3 and 4.
    British journal of pharmacology, 1998, Volume: 124, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Albuterol; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Endothelium, Vascular; Eosinophils; Humans; Lung; Neutrophils; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Thiophenes; Tumor Necrosis Factor-alpha

1998
Phosphodiesterase 3 inhibitors suppress oocyte maturation and consequent pregnancy without affecting ovulation and cyclicity in rodents.
    The Journal of clinical investigation, 1998, Aug-01, Volume: 102, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Contraceptive Agents, Female; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Estrus; Female; Fertilization; Heart Rate; Hypoxanthine; Isoenzymes; Meiosis; Menotropins; Mice; Mice, Inbred C57BL; Milrinone; Oogenesis; Ovarian Follicle; Ovulation; Ovulation Induction; Phosphodiesterase Inhibitors; Pregnancy; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Rolipram; Second Messenger Systems; Substrate Specificity; Thiophenes

1998
Phosphodiesterase expression in human epithelial cells.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Cell Line; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 1; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Lung; Phosphodiesterase Inhibitors; Purinones; Pyrrolidinones; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Thiophenes

1998
Phosphodiesterase 3 inhibitors selectively block the spontaneous resumption of meiosis by macaque oocytes in vitro.
    Human reproduction (Oxford, England), 2002, Volume: 17, Issue:8

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Feasibility Studies; Female; Macaca mulatta; Meiosis; Milrinone; Oocytes; Phosphodiesterase Inhibitors; Quinolones; Rolipram; Thiophenes

2002
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