Page last updated: 2024-09-03

fk 633 and aspirin

fk 633 has been researched along with aspirin in 2 studies

*Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) [MeSH]

*Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) [MeSH]

Compound Research Comparison

Studies
(fk 633)
Trials
(fk 633)
Recent Studies (post-2010)
(fk 633)
Studies
(aspirin)
Trials
(aspirin)
Recent Studies (post-2010) (aspirin)
190148,9476,81713,778

Protein Interaction Comparison

ProteinTaxonomyfk 633 (IC50)aspirin (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.35
Integrin beta-3Homo sapiens (human)5
Prostaglandin G/H synthase 1Ovis aries (sheep)0.8252
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)1.375
Integrin alpha-IIbHomo sapiens (human)5
Prostaglandin G/H synthase 1Homo sapiens (human)2.271
Substance-P receptorCavia porcellus (domestic guinea pig)2.4
Prostaglandin G/H synthase 2Homo sapiens (human)2.15
Urotensin-2 receptorRattus norvegicus (Norway rat)0.3
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)2.4
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.35
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4081

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aoki, T; Cox, D; Motoyama, Y; Seki, J; Senzaki, K; Takasugi, H; Tanaka, A1
Aoki, T; Honda, S; Okubo, M; Seki, J; Senzaki, K; Takahashi, F; Takasugi, H; Tanaka, A; Tomiyama, Y1

Other Studies

2 other study(ies) available for fk 633 and aspirin

ArticleYear
Comparison of the antithrombotic effects of FK633, GPIIb/IIIa antagonist, and aspirin in a guinea pig thrombosis model.
    Thrombosis research, 1998, Feb-01, Volume: 89, Issue:3

    Topics: Animals; Aspirin; Carotid Artery Thrombosis; Dipeptides; Fibrinolytic Agents; Guinea Pigs; Injections, Intravenous; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Tissue Plasminogen Activator

1998
Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis.
    Thrombosis and haemostasis, 1998, Volume: 79, Issue:6

    Topics: Adenosine Diphosphate; Antibodies, Monoclonal; Apyrase; Aspirin; Blood Platelets; Calcium; Cyclooxygenase Inhibitors; Dipeptides; Fibrinogen; Humans; Ion Transport; Peptide Fragments; Phenylacetates; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Signal Transduction; Sulfonamides; Thrombin; Thromboxane A2; Thromboxane B2; Tirofiban; Tyrosine

1998