Page last updated: 2024-09-05

biotin and colchicine

biotin has been researched along with colchicine in 13 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(colchicine)
Trials
(colchicine)
Recent Studies (post-2010) (colchicine)
14,847953,88215,4724042,974

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)colchicine (IC50)
Tubulin alpha-1A chainSus scrofa (pig)3.7639
Tubulin beta chainSus scrofa (pig)3.8663
Tubulin beta-4A chainHomo sapiens (human)2.4334
Tubulin beta chainHomo sapiens (human)2.7244
Tubulin alpha-3C chainHomo sapiens (human)2.4334
Serine/threonine-protein kinase pim-1Homo sapiens (human)4.3
Tubulin alpha-1B chainHomo sapiens (human)2.4334
Tubulin alpha-4A chainHomo sapiens (human)2.4334
Tubulin beta-4B chainHomo sapiens (human)2.4334
Vesicular acetylcholine transporterTetronarce californica (Pacific electric ray)2.62
Tubulin beta-3 chainHomo sapiens (human)2.4334
Tubulin beta-2A chainHomo sapiens (human)2.4334
Tubulin beta-8 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainBos taurus (cattle)2.8255
Tubulin alpha-3E chainHomo sapiens (human)2.4334
Tubulin alpha-1A chainHomo sapiens (human)2.4334
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.0611
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.1553
Tubulin alpha-1C chainHomo sapiens (human)2.4334
Tubulin beta-6 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainHomo sapiens (human)2.4334
Tubulin beta-1 chainHomo sapiens (human)2.4334

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Grant, WN; Lacey, E1
Kerkérian, L; Parent, A; Pelletier, G; Smith, Y1
Hannig, M; Moll, F1
Chalifour, LE; Dakshinamurti, K1
Chan, J; Pickel, VM1
Mock, DM; Zempleni, J1
Chiaia, NL; Goldstein, F; Rhoades, RW1
Barcia-González, J; Martínez-Soriano, F; Olucha-Bordonau, FE; Ruiz-Torner, A; Teruel, V; Valverde-Navarro, AA1
Akamatsu, M; Deyanat-Yazdi, G; Hayashi, Y; Kiso, Y; Kohno, K; Lloyd, GK; Neuteboom, S; Nicholson, B; Potts, B; Yamazaki, Y; Yasui, H1
Guan, Q; Li, Y; Wang, C; Wang, Z; Xing, D; Zhang, W; Zhang, Y1

Reviews

1 review(s) available for biotin and colchicine

ArticleYear
[Raney-nickel hydrogenolysis. Mechanism and pharmaceutical-chemical use].
    Mitteilungen. Deutsche Pharmazeutische Gesellschaft, 1970, Volume: 40, Issue:5

    Topics: Adenine; Benzene; Biotin; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Colchicine; Glycosides; Halogens; Hydantoins; Indicators and Reagents; Nickel; Nucleosides; Penicillin G; Pharmacopoeias as Topic; Steroids; Strychnine; Sulfonamides; Sulfones; Thiophenes

1970

Other Studies

12 other study(ies) available for biotin and colchicine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Photobiotin as a sensitive probe for protein labeling.
    Analytical biochemistry, 1987, May-15, Volume: 163, Issue:1

    Topics: Animals; Antigen-Antibody Reactions; Azides; Binding Sites; Biotin; Brain Chemistry; Colchicine; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Photochemistry; Proteins; Rosaniline Dyes; Sheep; Tubulin

1987
Distribution of neuropeptide Y immunoreactivity in the basal forebrain and upper brainstem of the squirrel monkey (Saimiri sciureus).
    The Journal of comparative neurology, 1985, Jun-01, Volume: 236, Issue:1

    Topics: Animals; Avidin; Basal Ganglia; Biotin; Brain Stem; Cerebral Cortex; Colchicine; Fluorescent Antibody Technique; Hippocampus; Histocytochemistry; Hypothalamus; Immunoenzyme Techniques; Nerve Tissue Proteins; Neuropeptide Y; Saimiri; Thalamus; Tissue Distribution

1985
The characterization of the uptake of avidin-biotin complex by HeLa cells.
    Biochimica et biophysica acta, 1982, Sep-13, Volume: 721, Issue:1

    Topics: Avidin; Biological Transport; Biotin; Colchicine; Cycloheximide; HeLa Cells; Humans; Kinetics; Ovalbumin; Pinocytosis; Procaine

1982
Met5-enkephalin is localized within axon terminals in the subfornical organ: vascular contacts and interactions with neurons containing gamma-aminobutyric acid.
    Journal of neuroscience research, 1994, Apr-15, Volume: 37, Issue:6

    Topics: Animals; Astrocytes; Avidin; Basement Membrane; Biotin; Cerebrovascular Circulation; Colchicine; Enkephalin, Methionine; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Neurons; Peroxidases; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Subfornical Organ

1994
Uptake and metabolism of biotin by human peripheral blood mononuclear cells.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Ammonium Chloride; Biological Transport; Biotin; Carbon Radioisotopes; Colchicine; Diglycerides; Endocytosis; Ethionine; Humans; In Vitro Techniques; Kinetics; Leukocytes, Mononuclear; Lithium Chloride; Ouabain; Sucrose; Temperature

1998
Effects of neonatal attenuation of axoplasmic flow or transection of the rat's infraorbital nerve on the morphology of individual trigeminal primary afferent terminals in the brainstem.
    Experimental neurology, 1999, Volume: 156, Issue:2

    Topics: Afferent Pathways; Animals; Animals, Newborn; Axonal Transport; Axons; Axotomy; Biotin; Cell Count; Colchicine; Nerve Endings; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion; Trigeminal Nerve; Trigeminal Nerve Injuries; Trigeminal Nuclei; Vibrissae; Vinblastine

1999
Cytoarchitecture and efferent projections of the nucleus incertus of the rat.
    The Journal of comparative neurology, 2003, Sep-08, Volume: 464, Issue:1

    Topics: Animals; Biotin; Brain Mapping; Cholecystokinin; Cholera Toxin; Choline O-Acetyltransferase; Colchicine; Dextrans; Fluorescent Dyes; Glutamate Decarboxylase; Gout Suppressants; Immunohistochemistry; Iontophoresis; Male; Mesencephalon; Neural Pathways; Neurons, Efferent; Phytohemagglutinins; Rats; Rats, Sprague-Dawley; Serotonin; Staining and Labeling; Time Factors; Tissue Distribution

2003
Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents.
    Chembiochem : a European journal of chemical biology, 2008, Dec-15, Volume: 9, Issue:18

    Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Colchicine; Diketopiperazines; Humans; Inhibitory Concentration 50; Photoaffinity Labels; Tubulin; Tubulin Modulators

2008
Design, synthesis, and biological evaluation of biotinylated colchicine derivatives as potential antitumor agents.
    Journal of enzyme inhibition and medicinal chemistry, 2022, Volume: 37, Issue:1

    Topics: Animals; Antineoplastic Agents; Biotin; Biotinylation; Cell Proliferation; Cells, Cultured; Colchicine; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Polymerization; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2022