Page last updated: 2024-09-02
2,3-bis(3'-hydroxybenzyl)butyrolactone and rofecoxib
2,3-bis(3'-hydroxybenzyl)butyrolactone has been researched along with rofecoxib in 1 studies
Compound Research Comparison
| Studies (2,3-bis(3'-hydroxybenzyl)butyrolactone) | Trials (2,3-bis(3'-hydroxybenzyl)butyrolactone) | Recent Studies (post-2010) (2,3-bis(3'-hydroxybenzyl)butyrolactone) | Studies (rofecoxib) | Trials (rofecoxib) | Recent Studies (post-2010) (rofecoxib) |
|---|---|---|---|---|---|
| 319 | 32 | 124 | 1,914 | 307 | 163 |
Protein Interaction Comparison
| Protein | Taxonomy | 2,3-bis(3'-hydroxybenzyl)butyrolactone (IC50) | rofecoxib (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | 0.43 | |
| Cytochrome c oxidase subunit 2 | Homo sapiens (human) | 1.51 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.5 | |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | 0.5 | |
| Calpain-2 catalytic subunit | Homo sapiens (human) | 0.02 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 1.8 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.3602 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 0.76 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 0.486 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.036 | |
| Sodium-dependent serotonin transporter | Macaca mulatta (Rhesus monkey) | 0.5 |
Research
Studies (1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Nijmeijer, SM; Ruchirawat, S; van den Berg, M; van Duursen, MB | 1 |
Other Studies
1 other study(ies) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and rofecoxib
| Article | Year |
|---|---|
Chemopreventive actions by enterolactone and 13 VIOXX-related lactone derivatives in H295R human adrenocortical carcinoma cells.
Topics: 4-Butyrolactone; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Cell Cycle; Cell Line, Tumor; Enzyme Induction; Flavonoids; Gene Expression; Humans; Lactones; Lignans; Mitogen-Activated Protein Kinase Kinases; Neoplasms, Hormone-Dependent; Phytoestrogens; Protein Processing, Post-Translational; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Sulfones | 2010 |