Page last updated: 2024-12-11

vinigrol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

vinigrol: structure given in first source; produced by Virgaria nigra [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5492644
MeSH IDM0155316

Synonyms (8)

Synonym
1,5-butanonaphthalene-4,8a(1h)-diol, 4,4a,5,6,7,8-hexahydro-8,9-dimethyl-3-(hydroxymethyl)-12-(1-methylethyl)-, (1r-(1-alpha,4-beta,4a-beta,5-alpha,8-beta,8a-beta,9s*,12s*))-
vinigrol
brn 5063688
antibiotic fr 900478
111025-83-3
3-(hydroxymethyl)-8,12-dimethyl-9-(propan-2-yl)-4,4a,5,6,7,8-hexahydro-1,5-butanonaphthalene-4,8a(1h)-diol
DTXSID40911944
(1s,2r,5s,6s,9s,10r,13s,14s)-12-(hydroxymethyl)-2,9-dimethyl-6-propan-2-yltricyclo[8.4.0.05,14]tetradec-11-ene-1,13-diol

Research Excerpts

Overview

Vinigrol is a natural diterpenoid with unprecedented chemical structure. It has driven great efforts into its total synthesis in the past decades.

ExcerptReferenceRelevance
"Vinigrol is a natural diterpenoid with unprecedented chemical structure, driving great efforts into its total synthesis in the past decades. "( Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.
Gao, H; Gao, S; Gao, Z; He, Y; Hu, Y; Jiang, Y; Li, Y; Wang, C; Wang, H; Wei, W; Yang, Z; Yao, X; Zhao, L; Zhao, Y, 2022
)
2.54
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (24)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (8.33)18.7374
1990's0 (0.00)18.2507
2000's12 (50.00)29.6817
2010's9 (37.50)24.3611
2020's1 (4.17)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 26.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index26.79 (24.57)
Research Supply Index3.22 (2.92)
Research Growth Index4.22 (4.65)
Search Engine Demand Index31.58 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (26.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (4.17%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other23 (95.83%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]