Page last updated: 2024-12-11
vinigrol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
vinigrol: structure given in first source; produced by Virgaria nigra [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 5492644 |
| MeSH ID | M0155316 |
Synonyms (8)
| Synonym |
|---|
| 1,5-butanonaphthalene-4,8a(1h)-diol, 4,4a,5,6,7,8-hexahydro-8,9-dimethyl-3-(hydroxymethyl)-12-(1-methylethyl)-, (1r-(1-alpha,4-beta,4a-beta,5-alpha,8-beta,8a-beta,9s*,12s*))- |
| vinigrol |
| brn 5063688 |
| antibiotic fr 900478 |
| 111025-83-3 |
| 3-(hydroxymethyl)-8,12-dimethyl-9-(propan-2-yl)-4,4a,5,6,7,8-hexahydro-1,5-butanonaphthalene-4,8a(1h)-diol |
| DTXSID40911944 |
| (1s,2r,5s,6s,9s,10r,13s,14s)-12-(hydroxymethyl)-2,9-dimethyl-6-propan-2-yltricyclo[8.4.0.05,14]tetradec-11-ene-1,13-diol |
Research Excerpts
Overview
Vinigrol is a natural diterpenoid with unprecedented chemical structure. It has driven great efforts into its total synthesis in the past decades.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Vinigrol is a natural diterpenoid with unprecedented chemical structure, driving great efforts into its total synthesis in the past decades. " | ( Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells. Gao, H; Gao, S; Gao, Z; He, Y; Hu, Y; Jiang, Y; Li, Y; Wang, C; Wang, H; Wei, W; Yang, Z; Yao, X; Zhao, L; Zhao, Y, 2022) | 2.54 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (24)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (8.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (50.00) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 26.79
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (26.79) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (4.17%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 23 (95.83%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||