tulipalin b

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

tulipalin B: RN given refers to (S)-isomer; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

tulipalin B : A member of the class of butan-4-olides that is 3-methylidenebutan-4-olide carrying an additional hydroxy substituent at position 4 (the 4R-enantiomer) [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID Source	ID
PubMed CID	162351
SCHEMBL ID	4922801
MeSH ID	M0140230

Synonyms (15)

Synonym
tulipalin b
38965-80-9
(4s)-4-hydroxy-3-methylideneoxolan-2-one
4-hydroxy-3-methylideneoxolan-2-one
15vwd3k2a9 ,
beta-hydroxy-alpha-methylene-gamma-butyrolactone
2(3h)-furanone, dihydro-4-hydroxy-3-methylene-, (s)-
unii-15vwd3k2a9
singleex tulipalin
2(3h)-furanone, dihydro-4-hydroxy-3-methylene-, (4s)-
tulipalin b [inci]
(s)-(-)-tulipalin b
SCHEMBL4922801
C21187
DTXSID30959815

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	2 (25.00)	18.7374
1990's	2 (25.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	4 (50.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.66 (24.57)
Research Supply Index	2.20 (2.92)
Research Growth Index	4.86 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
4-butyrolactone 4-Butyrolactone: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.. tetrahydrofuranone : Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring.. gamma-butyrolactone : A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.	3.52	8	butan-4-olide	metabolite; neurotoxin
glucose, (beta-d)-isomer beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages.	3.16	5	D-glucopyranose	epitope; mouse metabolite
alpha-methylene gamma-butyrolactone alpha-methylene gamma-butyrolactone : A butan-4-olide having a methylene group at the 3-position.	2.68	3	butan-4-olide	anti-ulcer drug; gastrointestinal drug
tuliposide a tuliposide A: RN given refers to (beta-D-Glucopyranose); RN for cpd without isomeric designation not available 2/90; found in the Alstroemeria plant	2.4	2	beta-D-glucoside; homoallylic alcohol; O-acyl carbohydrate
glycosides [no description available]	2.7	3
sodium oxybate Sodium Oxybate: The sodium salt of 4-hydroxybutyric acid. It is used for both induction and maintenance of ANESTHESIA.	2.4	2
6-tuliposide b 6-tuliposide B: has antibacterial activity; structure in first source. 6-tuliposide B : A 6-O-acyl-D-glucose in which the 6-acyl group is specified as (3S)-3,4-dihydroxy-2-methylidenebutanoyl. A secondary metabolite with potent antibacterial activity, occurring specifically in tulip anthers.	8.01	4	6-O-acyl-D-glucose; enoate ester	antibacterial agent; antifungal agent; plant metabolite

Condition	Relationship Strength	Studies
Allergic Contact Dermatitis [description not available]	2	1
Dermatitis, Occupational A recurrent contact dermatitis caused by substances found in the work place.	2	1
Hand Dermatosis [description not available]	2	1
Hand Dermatoses Skin diseases involving the HANDS.	2	1
Dermatitis, Allergic Contact A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.	2	1
Contact Dermatitis [description not available]	2.37	2
Dermatitis, Contact A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.	2.37	2

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